glycopeptides

Question 1

example of a glycopeptide is

Answer 1

vancomycin

Question 2

mechanism of action of vancomycin

Answer 2

binds to the end of the goring pentapeptide chain during peptidoglycan synthesis, preventing cross linking so it is bactericidal

Question 3

vancomycin is not

Answer 3

absorbed when given orally so must be given IV except in severe C. difficile where you give it oraly because you don’t want it to be systemically absorbed

Question 4

vancomycin is active

Answer 4

ONLY against gram positive organisms (feck all affect on gram negative organisms)

Question 5

toxic levels of vancomycin can occur

Answer 5

in those with kidney failure causing further kidney damage

Question 6

excretion of vancomycin

Answer 6

renal