M6 - Lesson 3: Central Dogma of Protein Synthesis – Replication, Transcription and Translation Flashcards

1
Q

The information stored in DNA is used to direct in _____

A

synthesis of proteins

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2
Q

It’s the process by which DNA makes a copy of itself when a cell divides.

A

Replication

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3
Q

It’s the ordered synthesis of RNA from DNA; the genetic information stored in DNA is passed onto RNA.

A

Transcription

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4
Q

It’s the synthesis of protein from RNA the genetic information determined the specific amino acid sequence of the protein.

A

Translation

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5
Q

The original DNA molecule forms ________________, each of which contains a strand from the parent DNA and one new strand.

A

two new DNA molecules

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6
Q

forms as the two strands split apart

A

replication fork

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7
Q

The identity of the bases on the temple strand determines the order of the bases on the new strand.

A

Replication

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8
Q

TRUE OR FALSE

A must pair with T, and G must pair with C.

A

True

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9
Q

It’s formed between the 5’-phhosphate of the nucleoside triphosphate and 3’-OH group of the new DNA strand.

A

new phosphodiester bond

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10
Q

Replication occurs in what direction on the temple strand, from the 3’ end to the 5’ end?

A

only one direction

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11
Q

What are the two new strand?

A

leading strand and lagging strand

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12
Q

growing continuously

A

leading strand

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13
Q

growing in small fragments

A

lagging strand

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14
Q

What is the monosaccharide in RNA?

A

Ribose

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15
Q

What is the base that is present in RNA?

A

the uracil (U)

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16
Q

RNA is a _____, and smaller than DNA.

A

single strand

17
Q

What are the three types of RNA molecules?

A
ribosomal RNA (rRNA)
messenger RNA (mRNA)
transfer RNA (tRNA)
18
Q

This provides the site where polypeptides are assembled during protein sysnthesis.

A

Ribosomal RNA (rRNA)

19
Q

carries the information from DNA to the ribosome.

A

Messenger RNA (mRNA)

20
Q

brings specific amino acids to the ribosomes for protein synthesis.

A

Transfer RNA (tRNA)

21
Q

tRNA is drawn as a __________ , with an acceptor stem at the 3’ end, which carries the needed amino acid, and an anticodon, which identifies the needed amino acid.

A

cloverleaf shape

22
Q

It’s synthesis of mRNA from DNA.

A

Transcription

23
Q

What are the DNA splits into two strands?

A

template strand

informational strand

24
Q

which is used to synthesize RNA

A

template strand

25
Q

Transcription proceeds from the ___________ end of the template

A

3’ end to the 5’

26
Q

Transcription forms a mRNA with a ____________ to the template DNA strand and an exact sequence as the informational DNA strand.

A

complementary sequence

27
Q

What is the difference between mRNA and the information DNA strand base on mRNA?

A

U replaces T

28
Q

This is to determine the oder of amino acids in the protein.

A

mRNA contains the sequence of codons

29
Q

This are Individual to the peptide chain.

A

tRNAs bring specific amino acids

30
Q

This provides the platform on which protein synthesis occurs.

A

rRNA contains binding sites

31
Q

mRNA; UCA

A

codon

32
Q

tRNA; AGU

A

anticodon

33
Q

amino acid; serine

A

amino acid

34
Q

What are the three main parts of translation?

A

initiation, elongation, and termination.

35
Q

It begins with mRNA binding to the ribosome.

A

Initiation

36
Q

The tRNA brings the first amino acid

A

codon AUG

37
Q

Proceeds as the next tRNA molecule delivers the next amino acid, and a peptide bond forms between the two amino acids.

A

Elongation

38
Q

Translation continues until a stop codon (UAA, UAG, or UGA) is reached, and the completed protein is released.

A

termination