Lymphoid Tissue Flashcards

1
Q

Dendritic cell alternate description

A

“professional” antigen presenting cell

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2
Q

What is the difference between a primary and secondary lymphatic nodule?

A

secondary lymphatic nodules contain a large germinal center

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3
Q

What organ is required for development of secondary lymphatic nodules?

A

thymus

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4
Q

T/F

Lymphatic nodules are found exclusively in the thymus

A

F

no lymphatic nodules are found in the thymus

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5
Q

Tonsils are an example of a _________ nodular lymphatic tissue

A

non-encapsulated

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6
Q

What component of lymph nodes is responsible for “filtering” the lymph?

A

macrophages

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7
Q

Reticular cells are also known as…

A

fibroblasts

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8
Q

These are the 3 components of lymph nodes

A

capsule
trabeculae
stroma

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9
Q

This component of lymph nodes contains lymphocytes

A

stroma (bodies are made of cells, right?)

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10
Q

What type of structural fiber is found at high concentrations in lymph nodes?

A

reticular fibers

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11
Q

Reticular fibers are made of what type of collagen?

A

type III

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12
Q

Which cell type lines the sinusoids of lymph nodes?

A

endothelial cells

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13
Q

This is an important attachment molecule in the blood-thymus barrier

A

desmosomes

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14
Q

This is an important attachment molecule in the blood-thymus barrier

A

desmosomes

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15
Q

Which type of lymphatic vessels are present in the spleen: afferent or efferent?

A

efferent only

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16
Q

The hilus of the spleen contains these structures

A

afferent/efferent blood vessels
efferent lymph vessels
sympathetic nerves

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17
Q

What are trabeculae in the spleen?

A

invaginations of connective tissue capsule in pulp-containing regions

18
Q

Periarterial lymphatic sheaths are found in red/white pulp of spleen

A

white

19
Q

Periarterial lymphatic sheaths contain primarily B-/T-cells

A

T-cells

20
Q

Splenic/lymphatic nodules contain primarily B-/T-cells

A

B-cells

21
Q

Two important but difficult to see structures in splenic red pulp

A
splenic sinuses
splenic cords (Billroth cords)
22
Q

The marginal red pulp zone contains what type of arteries?

A

follicular arteries–branches of central arteries

23
Q

The marginal red pulp zone contains what type of arteries?

A

follicular arteries–branches of central arteries

24
Q

What is the function of the marginal zone?

A

this is where lymphoid cells leave blood circulation

25
Q

Terminal capillaries open into sinusoids in this type of lymph circulation

A

closed

26
Q

Terminal capillaries open into red pulp in this type of lymph circulation

A

open

27
Q

Open/closed lymph circulation predominates in humans

A

open

28
Q

What does the spleen have to do with iron?

A

the spleen recovers iron from RBC Hb

29
Q

What does the spleen have to do with iron?

A

the spleen recovers iron from RBC Hb

30
Q

The thymus has afferent/efferent/both lymphatic vessels

A

efferent only

31
Q

When is the thymus the largest (relatively)?

A

first 2 yr of life

32
Q

The thymus increases in size until

A

puberty

33
Q

The thymus is derived from…

A

3rd branchial pouch (endoderm)

34
Q

The thymus is derived from which embryonic layer?

A

endoderm

35
Q

The thymus is composed of which lobule type?

A

incomplete

36
Q

Lymphocytes enter they thymus small/large

A

large

37
Q

Lymphocytes enter the peripheral/central thymus

A

peripheral

38
Q

As lymphocytes mature in thymus, they become larger/smaller

A

smaller

39
Q

As lymphocytes mature in the thymus, they move centrally/peripherally

A

centrally

40
Q

Hassall’s corpuscles are seen in which organ?

A

medulla of thymus