Lymphoid Tissue Flashcards

1
Q

Dendritic cell alternate description

A

“professional” antigen presenting cell

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2
Q

What is the difference between a primary and secondary lymphatic nodule?

A

secondary lymphatic nodules contain a large germinal center

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3
Q

What organ is required for development of secondary lymphatic nodules?

A

thymus

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4
Q

T/F

Lymphatic nodules are found exclusively in the thymus

A

F

no lymphatic nodules are found in the thymus

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5
Q

Tonsils are an example of a _________ nodular lymphatic tissue

A

non-encapsulated

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6
Q

What component of lymph nodes is responsible for “filtering” the lymph?

A

macrophages

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7
Q

Reticular cells are also known as…

A

fibroblasts

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8
Q

These are the 3 components of lymph nodes

A

capsule
trabeculae
stroma

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9
Q

This component of lymph nodes contains lymphocytes

A

stroma (bodies are made of cells, right?)

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10
Q

What type of structural fiber is found at high concentrations in lymph nodes?

A

reticular fibers

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11
Q

Reticular fibers are made of what type of collagen?

A

type III

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12
Q

Which cell type lines the sinusoids of lymph nodes?

A

endothelial cells

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13
Q

This is an important attachment molecule in the blood-thymus barrier

A

desmosomes

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14
Q

This is an important attachment molecule in the blood-thymus barrier

A

desmosomes

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15
Q

Which type of lymphatic vessels are present in the spleen: afferent or efferent?

A

efferent only

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16
Q

The hilus of the spleen contains these structures

A

afferent/efferent blood vessels
efferent lymph vessels
sympathetic nerves

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17
Q

What are trabeculae in the spleen?

A

invaginations of connective tissue capsule in pulp-containing regions

18
Q

Periarterial lymphatic sheaths are found in red/white pulp of spleen

19
Q

Periarterial lymphatic sheaths contain primarily B-/T-cells

20
Q

Splenic/lymphatic nodules contain primarily B-/T-cells

21
Q

Two important but difficult to see structures in splenic red pulp

A
splenic sinuses
splenic cords (Billroth cords)
22
Q

The marginal red pulp zone contains what type of arteries?

A

follicular arteries–branches of central arteries

23
Q

The marginal red pulp zone contains what type of arteries?

A

follicular arteries–branches of central arteries

24
Q

What is the function of the marginal zone?

A

this is where lymphoid cells leave blood circulation

25
Terminal capillaries open into sinusoids in this type of lymph circulation
closed
26
Terminal capillaries open into red pulp in this type of lymph circulation
open
27
Open/closed lymph circulation predominates in humans
open
28
What does the spleen have to do with iron?
the spleen recovers iron from RBC Hb
29
What does the spleen have to do with iron?
the spleen recovers iron from RBC Hb
30
The thymus has afferent/efferent/both lymphatic vessels
efferent only
31
When is the thymus the largest (relatively)?
first 2 yr of life
32
The thymus increases in size until
puberty
33
The thymus is derived from...
3rd branchial pouch (endoderm)
34
The thymus is derived from which embryonic layer?
endoderm
35
The thymus is composed of which lobule type?
incomplete
36
Lymphocytes enter they thymus small/large
large
37
Lymphocytes enter the peripheral/central thymus
peripheral
38
As lymphocytes mature in thymus, they become larger/smaller
smaller
39
As lymphocytes mature in the thymus, they move centrally/peripherally
centrally
40
Hassall's corpuscles are seen in which organ?
medulla of thymus