Circulating Blood-Downing

Question 1

Serum =

Answer 1

plasma - clotting proteins

Question 2

Normal erythrocyte count in males and females

Answer 2

males: 5x10^6/mm3
females: 4.5x10^6/mm3

Question 3

RBC diameter

Answer 3

7.7 µm

Question 4

RBC energy

Answer 4

anaerobic glycolysis and pentose phosphate pathway

Question 5

Roulous

Answer 5

stacked RBCs on slides

Question 6

Lifespan of RBCs

Answer 6

120-130 days

Question 7

Lifespan of platelets

Answer 7

8-10 days

Question 8

Normal platelet count

Answer 8

400,000/mm3

Question 9

Megakaryocytes are found

Answer 9

in bone marrow

Question 10

Two areas of platelets

Answer 10

granulomere (central)

hyalomere (peripheral)

Question 11

Lamba granules of platelets contain

Answer 11

lysosomes

Question 12

Diapedesis occurs most commonly in this area

Answer 12

post-capillary venule

Question 13

Granulocytes

Answer 13

neutrophils
basophils
eosinophils

Question 14

Agranulocytes

Answer 14

monocytes

lymphocytes

Question 15

Neutrophil amount in differential

Answer 15

50-70%

Question 16

Nuclei of neutrophils

Answer 16

muli-lobed

Question 17

Azurophilic granules in neutrophils

Answer 17

primary: 20%
reddish purple
contain myeloperoxidases

Question 18

Neutrophilic granules

Answer 18

specific: 80%

Hydrolases active at neutral or alkaline pH

Question 19

2 killing mechanisms of neutrophils

Answer 19

• enzymatic

- reactive oxygen species production

Question 20

Neutrophilic granule function

Answer 20

bacteriocidal

Question 21

Azurophilic granule function

Answer 21

bacterial digestion

Question 22

What enzyme produces reactive oxygen species in lysosomes?

Answer 22

NADPH oxidase

Question 23

Eosinophil differential count

Answer 23

1%

Question 24

Eosinophil nucleus

Answer 24

bilobular

Question 25

Which amino acid is high in eosinophils?

Answer 25

arginine

Question 26

Eosinophils contain these two crystalline substructures

Answer 26

major basic protein

eosin

Question 27

Eosinophils contain these to crystalline substructures

Answer 27

major basic protein

eosinophilic cationic protein

Question 28

What to eosinophils fight?

Answer 28

• allergies
• inflammatory reactions
• parasitic worm invasions

Question 29

Basophil differential

Answer 29

0.5%

Question 30

Basophil nucleus

Answer 30

difficult to see

Question 31

Basophil function

Answer 31

initiate allergic and inflammatory responses–similar to mast cells

Question 32

Basophil function

Answer 32

initiate allergic and inflammatory responses–similar to mast cells

Question 33

Basophils have Fc receptors for fragments of

Answer 33

IgE

Question 34

Granulocytes are mitotic/amitotic in blood

Answer 34

amitotic

Question 35

Lymphocytes are mitotic/amitotic in blood

Answer 35

mitotic

Question 36

Lymphocyte differential %

Answer 36

20-40%

Question 37

Types of lymphocytes

Answer 37

B-cells
T-cells
NK-cells

Question 38

B-cell fates

Answer 38

Plasma cells –> antibodies

Memory B-cells

Question 39

B-cell lymphocyte %

Answer 39

15%

Question 40

T-cell lymphocyte %

Answer 40

80-90%

Question 41

3 type of T-cells

Answer 41

CD4+ helper T-cells
CD8+ cytotoxic T-cells
supressor T-cells

Question 42

NK cell functions

Answer 42

kill virally infected and neoplastic cells

Question 43

Monocyte differential %

Answer 43

2-8%

Question 44

Monocyte nucleus

Answer 44

kidney-bean shaped, vacuoles seen in cytoplasm

Question 45

Granulocytes in lymph indication

Answer 45

underlying pathology

Question 46

Lymph coagulates quickly/slowly

Answer 46

slowly

Question 47

Is lymph highly oxygenated?

Answer 47

no

Question 48

Chylomicrons

Answer 48

fat + plasma proteins

Question 49

Hemoconia

Answer 49

plasma “junk”

Question 50

Blood cells exit BM through

Answer 50

sinusoidal capillaries