Hematopoietic Tissue-Downing Flashcards

1
Q

What are the types of hematopoietic tissue?

A

myeloid and lymphatic

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2
Q

Where is myeloid tissue located?

A

medullary cavity of bones

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3
Q

Where is lymphatic tissue located?

A

lymph organs: thymus, lymph nodes, spleen, non-encapsulated lymph organs

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4
Q

What tissue type is hematopoietic tissue derived from?

A

mesenchyme (except thymus)

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5
Q

From which embryonic structure is hematopoietic tissue derived from?

A

yolk sac

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6
Q

Colony forming units

A

from yolk sac

form hematopoietic outposts in liver, spleen, and bone

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7
Q

Major site of blood formation during fetal life

A

liver

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8
Q

Which bone is first to develop a medullary cavity for myeloid tissue?

A

clavicle

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9
Q

Extramedullary myelopoiesis

A

pathological

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10
Q

Two types of bone marrow

A

yellow: mostly fat, can be converted
red: site of hematopoiesis

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11
Q

Two components of myeloid tissue

A

parenchyma: fibroblasts, macrophages, fat-storing cells, osteogenic cells
stroma: collagenous fibers, reticular fibers (type III collagen)

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12
Q

What type of capillaries permit red and white cells to enter circulation

A

sinusoidal

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13
Q

How many RBCs are produced per second?

A

1.5 million

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14
Q

How long do RBCs need to mature

A

1 wk

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15
Q

Bast cells (RBC) nuclei

A

multiple nucleoli on progenitor cells, negatively stained

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16
Q

Myeloblast and erythroblast common features

A

large nuclei with nucleoli

rims of basophilic cytoplasm

17
Q

Granulocyte order of differentiation

A
CFU
Myeloblast
Pro-myelocyte
Myelocyte (differentiated)
Metamyelocyte (amitotic)
Band cell
Mature cell
18
Q

Both T- and B-cells populate __________ after they are formed in the thymus and bone marrow, respectively

A

secondary lymphoid organs