Lymphocyte Activation Flashcards

1
Q

Th1 dominant leprosy

A
Tubercoid leprosy
Low levels of organism, low infectivity
Granulomas and local inflammation
Normal serum Ig levels
Normal T cell responsiveness, response to leprae infection
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2
Q

Th2 dominant leprosy

A

Lepromatous leprosy
Large amount of organism growth, high infectivity
Disseminated infection
Hypergammaglobulinemia
Low/absent T cell responsiveness, no response to infection

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