DSA Biomolecules Flashcards

1
Q

Normal blood glucose levels when fasting or fed

A

70-100mg/dL fasting

Up to 140 when fed

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2
Q

Diabetes blood glucose levels

A

> 126mg/dL fasting

>199mg/dL fed

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3
Q

Hypoglycemic blood glucose level and deadly blood glucose level

A

<60mg/dL hypoglycemic

<40mg/dL convulsions/coma/brain damage/death

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4
Q

Sugar alcohols cause cataracts, retinopathy and peripheral neuropathy how?

A

Glucose may be converted to sorbitol, which is osmotically active and triggers the movement of water into cells, where it accumulates

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5
Q

Explain lactose intolerance

A

It is a genetic deficiency in the gut enzyme lactase

Microbial fermentation of lactose in the gut will occur and cause gas/diarrhea

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6
Q

Isoprenoid lipids include

A

Steroids: Cholesterol, Steroid hormones, bile acids
Lipid soluble vitamins A, D, E, K
Coenzyme Q

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7
Q

Difference between w-3 and w-6 fatty acids

A

w-3 have last double bond 3 carbons away from end

w-6 last double bond is 6 carbons away from end

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8
Q

What causes gallstones, what can help treat

A

When bile contains too much cholesterol and too little bile salt, the cholesterol hardens into pebble-like solids called gallstones
Treated with chenodeoxcholic acid

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9
Q

What happens to the nitrogen in proteins after they are metabolized

A

It is excreted as urea

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10
Q

How many grams of protein are degraded and synthesized each day in a typical human

A

400g each

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11
Q

Where does oxidation of the SH group in cysteine take place to form a disulfide bond, and why does it occur there

A

In the lumen of the rough ER, because there is glutathione in the cytoplasm which is a strong antioxidant

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