Lymphedema

Question 1

Lymphedema

Answer 1

An accumulation of protein - rich fluid in the interstitial spaces leading to the chronic inflammation and fibrosis in the affected tissues

Question 2

What is the lymphatic system?

Answer 2

-One way system that starts blindly in the interstitium
-Open system/ no central pump/ no valves
-Garbage disposal and recycling system
-Responsible for maintain aging fluid homeostasis by managing interstitial fluid and mobilizing waste products
-Recycles plasma proteins back into bloodstream
-Absorbs and transports lipids and fatty acids to the circulatory system
-Transports antigens, antigen-presenting cells, and other immune cells to the lymph nodes where adaptive immunity is stimulated

Question 3

Regional lymph nodes

Answer 3

Cervical lymph nodes

Axillary lymph nodes

Inguinal lymph nodes

Question 4

Lymphatic capillaries

Answer 4

Single layer of endothelial cells; may overlap or lay close to each other

When we swell, valves are pulled apart to allow fluid into lymphatic capillaries

Question 5

Lymph nodes

Answer 5

Functions
1. Protective: filters harmful material in lymph fluid
2. Immune: lymph nodes produce antigen-stimulated lymphocytes
3. Thickening of lymph fluid

Question 6

Lymphatic trunks

Answer 6

Thoracic duct - Originates anterior to vertebrae t11-L2

Follows similar path to arterial and venous flow

Question 7

What makes up lymphatic system?

Answer 7

Proteins
Water
Cells
Fat (only in digestive system)

Superficial through the skin layer

Each organ has its own lymphatic structure