lymphatics Flashcards
location of the spleen
left hypochondrium
rib 10-11
spleen develops from
intreperitoneal organ of the foregut
- not derived from gut tube
- developed from LP-M
spleen held to stomach by
mesentery - gastrosplenic ligament
size of spleen
variable
spleen held to posterior body wall by
mesentery - splenorenal ligament
blood supply to the spleen
arterial - celiac artery (splenic artery part)
venous - splenic vein (drains to portal view because it is unpaired)
embryonic function of the spleen
ethrypoietic organ
becomes filter/immune after
spleen functions post birth
mainly lymphoid organ
filters RBC
antigen presentation and immune response
histology of the spleen
fibrous thin capsule
thin and wrapped in peritoneum
- dense irregular CT that send trabecular into the organ
trabecular connected by
reticular fibres
significance of capsule and trabecular
prone to rupture
white pulp of the spleen
20% of splenic volume
splenic arterial branches between the trabeculae
end branches have
peri arteriolar lymphoid sheaths
lots f T lymphocytes in the tunica externally (outside of the cells)
lymphoid nodules
germinal centres
dense zone of aggregating and proliferting T lymphocytes
central artery
in germinal centre
not central
marginal zone
small arterioles and capillaries branch out into marginal zone
area where the blood vessels are moving more toward the red pulp