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Haematology > Lymphadenopathy and Lymphoma > Flashcards

Lymphadenopathy and Lymphoma Flashcards

1
Q

Give some differentials for lymphadenopathy

A

Infection
Metastatic cancer
Connective tissue disease
Lymphoma

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2
Q

Give some general symptoms of lymphoma

A

Drenching night sweats
Weight loss
Itch without rash
Alcohol-induced pain (in lump)

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3
Q

Describe the appearance of a lump caused by lymphoma

A

Non-tender
Smooth
Soft

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4
Q

What first-line investigation should be done for lymphoma?

A

Biopsy (core biopsy/FNA insufficient)

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5
Q

What is involved in immunohistochemistry?

A

Pattern of proteins on surface of lymphoma cells analysed

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6
Q

What is involved in cytogenetic analysis?

A

Specific pattern of of chromosome abnormalities are looked for in lymphomas

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7
Q

What is involved in molecular analysis?

A

Patterns of gene expression are analysed

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8
Q

What are the three main categories of lymphoma?

A

Hodgkin’s
T cell non-Hodgkins
B cell non-Hodgkins

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Haematology (19 decks)

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