Lymphadenopathy Flashcards

1
Q

What is the INDAM causes of lymphadenopathy?

A
  • infective
  • neoplasm
  • drugs
  • autoimmune
  • metabolic
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2
Q

Potential symptoms associated with lymphadenopathy?

A
  • lump
  • fever
  • weight loss
  • itch without a rash
  • alcohol induced pain
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3
Q

Tender lymph node may be due to what?

A
  • viral

- bacteria

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4
Q

A firm lymph node may be due to what?

A
  • viral

- bacteria

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5
Q

A hard lymph node with irregular surface may be caused by what?

A
  • metastatic carcinoma
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6
Q

How can CLL be diagnosed

A
  • lymphocytosis on FBC

- Increased WCC

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7
Q

What are B symptoms?

A
  • fever
  • weight loss
  • night sweats
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8
Q

Alcohol induce node pain may be a sign of what?

A
  • lymphoma
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9
Q

When staining for antibodies on a lymph node biopsy a brown colour indicates?

A
  • positive

- blue = negative

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10
Q

2 main lymphoma categories?

A
  • hodgkin

- non - hodgkin (mainly B cell)

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11
Q

Risk factors for lymphoma?

A
  • immunosuppression
  • autoimmune
  • infections
  • genetic
  • environment
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12
Q

What staging system is used in both non-hodgkin and hodkin lymphoma and what does it involve?

A
  • Ann Arbor staging

- location of affected lymph nodes

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13
Q

What is commoner? Hodgkin or non-hodgkin

A
  • non- hodgkin
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14
Q

What cells appear on hodgkin staining?

A
  • reed-sternberg
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15
Q

Treatment of Hodgkin lymphoma?

A
  • chemotherapy
  • radiotherapy
  • immunotherapy
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16
Q

Treatment of non-hodgkin lymphoma

A
  • radiotherapy
  • chemotherapy
  • monoclonal antibodies
17
Q

When might steroids be used in lymphoma?

A
  • good affect on lymphoma
  • may be used in emergency
  • best to biopsy prior to steroid
18
Q

Burkitt lymphoma is a ____ lymphoma?

A
  • non-hodgkin
19
Q

Burkitt lymphoma is associated with what?

A
  • EBV

- HIV

20
Q

How might burkitt lymphoma present

A
  • jaw

- abdo tumour

21
Q

What causes burkitt lymphoma?

A
  • chromosomal translocation of c-myc