Lymphadenopathy Flashcards
What is the INDAM causes of lymphadenopathy?
- infective
- neoplasm
- drugs
- autoimmune
- metabolic
Potential symptoms associated with lymphadenopathy?
- lump
- fever
- weight loss
- itch without a rash
- alcohol induced pain
Tender lymph node may be due to what?
- viral
- bacteria
A firm lymph node may be due to what?
- viral
- bacteria
A hard lymph node with irregular surface may be caused by what?
- metastatic carcinoma
How can CLL be diagnosed
- lymphocytosis on FBC
- Increased WCC
What are B symptoms?
- fever
- weight loss
- night sweats
Alcohol induce node pain may be a sign of what?
- lymphoma
When staining for antibodies on a lymph node biopsy a brown colour indicates?
- positive
- blue = negative
2 main lymphoma categories?
- hodgkin
- non - hodgkin (mainly B cell)
Risk factors for lymphoma?
- immunosuppression
- autoimmune
- infections
- genetic
- environment
What staging system is used in both non-hodgkin and hodkin lymphoma and what does it involve?
- Ann Arbor staging
- location of affected lymph nodes
What is commoner? Hodgkin or non-hodgkin
- non- hodgkin
What cells appear on hodgkin staining?
- reed-sternberg
Treatment of Hodgkin lymphoma?
- chemotherapy
- radiotherapy
- immunotherapy
Treatment of non-hodgkin lymphoma
- radiotherapy
- chemotherapy
- monoclonal antibodies
When might steroids be used in lymphoma?
- good affect on lymphoma
- may be used in emergency
- best to biopsy prior to steroid
Burkitt lymphoma is a ____ lymphoma?
- non-hodgkin
Burkitt lymphoma is associated with what?
- EBV
- HIV
How might burkitt lymphoma present
- jaw
- abdo tumour
What causes burkitt lymphoma?
- chromosomal translocation of c-myc
