Blood transfusion Flashcards
1
Q
What is blood screened for before donor transfusion?
A
- HIV
- Hep E
- Hep C
- Hep B
- HTLV
- Syphillis
2
Q
How long can red cells be stored for?
A
- 35 days
3
Q
How long can FFP be stored for?
A
- 3 years frozen
4
Q
How long can platelets be stored for?
A
- 7 days
5
Q
Explain red cell antigens?
A
- inherited from parents
- foreign antigen -> antibody formation
- 2nd exposure can cause reaction
6
Q
Explain the ABO system?
A
- chromosome 9
- 2 copies
- a and b cause h substance
- o is silent
7
Q
What is Landsteiner’s law?
A
- when someone lacks A or B antigen
- exposure to natural antigen can cause antibody formation
8
Q
ABO blood types?
A
- A
- B
- AB
- O
9
Q
Antibiodies for each ABO group
A
- A = anti b
- B = anti a
- AB = neither
- o = anti a and anti b
10
Q
Donor group O can be given to what recipient groups?
A
- O
- A
- B
- AB
- As no antigens present
11
Q
Donor group A can be given to what recipient groups?
A
- Group A
- AB
12
Q
Explain the Rh system
A
- 2 alleles D and d
- d is silent
- anti-d antibody can cause reaction
13
Q
Explain antisera
A
- known antibody specificity to identify antigens present on red cell
14
Q
Explain reagent red cells
A
- red cells of known antigen specificity to identify antibodies in plasma
15
Q
How is ABO grouping performed?
A
- antisera (identifying antigens)
- reagent red cells (identifying antibodies)
