Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hugh's MD2 Gen Med > Lung Pathology > Flashcards

Lung Pathology Flashcards

1
Q

In what percentage of patients does progressive TB occur?

A

Less than 10% of all TB patients, usually immunosuppressed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

What are some DDx of bilateral hilar enlargement?

A

Sarcoidosis

Lymphoma

TB

Metastasis

Other infections - fungal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

What is honeycomb lung?

A

Irreversible end-stage manifestation of a large number of interstitial inflammatory and proliferative lung diseases

Poor prognosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

What is the pathogenesis of an exudate?

A

Altered permeability of or damage to the capillaries surrounding space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are some non-infectious causes of pleuritis?

A

Trauma

Infarction

Connective tissue disorders: eg RA or lupus

Uraemia

Tumour

Radiation effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is a common cause of mesothelioma?

A

Asbestos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is sarcoidosis?

A

Most common interstitial lung disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is a common first presentation of mesothelioma?

A

Pleural effusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What type of TB typically occurs at the apex of the lung?

A

Secondary TB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are common causes of interstitual lung disease?

A

Idiopathic

Occupational/environmental exposure

Drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is secondary TB?

A

Reactivation of a dormant focus of primary TB

or a new infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the pathophysiology of mesothelioma?

A

Small fibres in the alveolar causes chronic stimulation > tumour develops

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is granulomatous inflammation?

A

Nodular clusters of macrophages +/- giant cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the commonest cause of non-necrotising granulomas?

A

Sarcoidosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are differentials for granulomatous inflammation?

A

TB

Sarcoid

Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is Gohn’s complex?

A

Gohn focus - TB lesion in the lung parenchyma

TB Lesion in a draining LN

16
Q

What must you do before treating sarcoidosis?

A

Exclude infective causes as steroids will likely exacerbate the sarcoidosis

17
Q

What is the prognosis of mesothelioma?

A

Average survival from onset of symptoms is 12-15 months

Mortality is 100%

18
Q

What causes a chylous effusion?

A

High lymphocyte count - TB, lymphoma

20
Q

How much fluid accumulation consitutes a pleural effusion?

A

>15mL

21
Q

Typical presentation of interstitial lung disease?

A

Slow, increasing SOB

Dry cough

22
Q

What is usual interstitial pneumonia?

A

Idiopathic pulmonary fibrosis

Cryptogenic fibrosing alveolitis

23
Q

How do you differentiate adenocarcinoma with mesothelioma?

A

IHC staining

24
Q

What is the difference between a transudate and exudate?

A

Transudate is lower in protein

25
Q

What is the pattern of location of sarcoidosis?

A

Enlarged lymphadenopathy at the hilum

Bilateral granulomatous inflammation of lungs

26
Q

What is the main differential for mesothelioma?

A

Adenocarcinoma

Hugh's MD2 Gen Med (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions