Lung and Pleura Flashcards

1
Q

Type of atelectasis with contralateral tracheal deviation

A

Compression

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2
Q

Type of atelectasis that is irreversible

A

Contraction (from pulmo or pleural fibrosis)

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3
Q

Type of pulmonary edema fluid if cardiogenic

A

Transudate

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4
Q

Type of pulmonary edema fluid if non-cardiogenic

A

Exudate

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5
Q

Histologic manifestation of ARDS/ALI

A

Diffuse alveolar damage (DAD)

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6
Q

Used to determine enlargement of mucous-secreting glands and goblet cell hyperplasia in chronic bronchitis

A

Reid index >0.4

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7
Q

More common type of emphysema

A

Centriacinar (caused by smoking)

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8
Q

Less common type of emphysema associated with alpha-1 antitrypsin defieciency

A

Panacinar

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9
Q

COPD can manifest as either primarily ___

A

Emphysematous (pink puffers) or bronchitis (blue bloaters)

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10
Q

Type of COPD (blue bloater or pink puffer) that manifests with mild dyspnea, copious sputum, and cor pulmonale is present

A

Predominant bronchitis

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11
Q

Defined as the occlusion of bronchi and bronchioles by thick, tenacious mucous plugs in this pulmonary disease caused by hyperreactive airways

A

Status asthmaticus

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12
Q

Histologic findings in status asthmaticus

A

Curshmann spirals and Charcot-Leyden crystals

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13
Q

Difference between emphysema and bronchiectasis

A

Emphysema has irreversible destruction of air spaces DISTAL to terminal bronchioles while bronchiectasis has destruction of smooth muscle and elastis tissue by chronic necrotizing infections leading to permanent dilation of BRONCHI AND BRONCHIOLES; emphysema less sputum, bronchiectasis more sputum

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14
Q

Also known as primary ciliary dyskinesia, associated with bronchiectasis

A

Kartagener’s syndrome

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15
Q

Hallmark of idiopathic pulmonary fibrosis

A

Patchy interstitial fibrosis with varying age

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16
Q

Early lesion of IPF

A

Fibroblastic focus

17
Q

Late lesion of IPF

A

Honeycomb fibrosis

18
Q

Most common pneumoconiosis in the world

A

Silicosis (crystalline silicon dioxide, most commonly quartz)

19
Q

Radiographic appearance of silicosis

A

Eggshell calcifications of lymph nodes

20
Q

Form of asbestos that lodges at distal airways near the pleura

A

Amphibole (vs serpentine chrysotile form)

21
Q

Found in sarcoidosis, a non-caseating granulomatous disease of unknown etiology

A

Schaumann bodies and asteroid bodies

22
Q

Organs affected in sarcoidosis

A

Lymph nodes (almost all), lungs, and spleen

23
Q

Definition of pulmonary HTN

A

Mean PA pressure of 25 mmHg or more at rest

24
Q

Type of pneumonia with red hepatization, gray hepatization, and resolution

A

Lobar pneumonia (vs bronchopneumonia with patchy infiltrates)

25
Q

Most common cause of lung abscess

A

Aspiration of infective material

26
Q

Etiologic agents of diffuse infiltrates in PICH

A

CMV, PCP, drug reaction

27
Q

Incidence of lung carcinoma subtypes

A

Adeno > squamous > small cell

28
Q

Lung CA association with smoking

A

Small cell > squamous > adeno

29
Q

Paraneoplastic syndrome associated with squamous lung CA

A

Hypercalcemia (PTHrP)

30
Q

Paraneoplastic syndrome associated with small cell lung CA

A

SIADH and cushing (ACTH)

31
Q

Precursor lesion of lung adenoCA

A

Atypical adenomatous hyperplasia

32
Q

Precursor lesion of small cell lung CA

A

NONE

33
Q

Morphology associated with small cell lung CA

A

Azzopardi effect

34
Q

Lung CA paraneoplastic syndrome associated with autoantibodies vs neuronal calcium channels

A

Lambert Eateon Myasthenic Syndrome (LEMS)

35
Q

Normal volume of pleural fluid

A

15 ml

36
Q

Non-inflammatory pleural effusions

A

Hydrothorax, hemothorax, and chylothorax