Lp 59 Flashcards
Kidneys filter blood &
Remove waste, toxins, excess water & ions
3 fluids are involved in the movement of fluid
-blood
-glomerular filtrate
-urine
3 processes in urine formation
-glomerular filtration
-tubular reabsorption
-tubular secretion
-major site of reabsorption
-transport of nutrients & ions
-permeable to h2o
-many mitochondria
-dense microvilli
-little secretion
PCT
-reabsorption of h20
-transport of ions
Loop of Henle
-reabsorption of h20
-reabsorption of ions
DCT
-reabsorption of h20
-transport of ions
-secretion of excess ions
Collecting duct
2 types of nephrons depending on location of loop of henle
-cortical nephrons (85%)
-juxtamedullary nephrons
-HP- passive process
-facilitated by 2 factors: high membrane permeability & increased glomerular BP
Glomerular filtration
How much fluid passes through glomerular membrane means?
Net filtration P (NFP)
Amt do fluid passing through glomerular membrane per minute means?
Glomerular filtration rate (GFR)
-reabsorption of h20 & other substances via tight junctions
-reabsorbed substances pass through or b/w tubule cells, through IF & into blood
-reabsorption of h20 & substances via passive & active transport
-diffusion of anions w/ cation movement
-osmosis follows reabsorption of ions (solvent drag)
-substance transport depends on no. Of carrier molecules inc ell membrane
Tubular reabsorption
-h20 via passive transport
-substances via active transport or facilitated diffusion
-reabsorption occurs at different sites of nephron
Tubular reabsorption of solutes
Tubular secretion substances are
-removed from peritubular capillaries
-returned to tubule to be excreted in urine
-clears H+, K+, creatinine, NH+4 from plasma
Tubular secretion is important for
-blood pH
-plasma K+ levels
-removing urea & urine acid
-removing drugs
