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Urinary > Loop of Henle > Flashcards

Loop of Henle Flashcards

1
Q

What is the osmolarity in the proximal tubule?

A

300mmoles

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2
Q

Whats is the osmolarity at the ascending loop?

A

100mmoles

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3
Q

What is the osmolarity of plasma?

A

300 mmoles

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4
Q

Where are the distal & proximal tubules found?

A

Cortex

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5
Q

What is the mechanism by which urine is concentrated?

A

Countercurrent multiplier

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6
Q

What is the maximum concentration of urine?

A

1200-1400mOsm

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7
Q

What is the minimum obligatory water loss?

A

500mls

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8
Q

What is the minimum concentration of urine?

A

30-50mOsm

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9
Q

What is actively co-transported out the tubule at the ascending limb?

A

NaCl

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10
Q

What is the ascending limb impermeable to?

A

Water

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11
Q

What is the descending limb permeable to?

A

Water

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12
Q

Where does water in the interstitium move to?

A

Vasa recta

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13
Q

The tubule is progressively____ as it moves down the descending limb

A

concentrated

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14
Q

The tubule is progressively _____ as it moves up the ascending limb

A

diluted

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15
Q

In the LoH, what is the horizontal gradient observed between the ascending limb & interstium?

A

200 msom

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16
Q

What is the vertical gradient in the interstiium?

A

300>1200mOsm

17
Q

What occurs at the collecting duct? Regulated by?

A

Water reabsorption

ADH

18
Q

In the presence of frusemide, what is the osmolarity of urine?

A

300mOsm

Isotonic

19
Q

What do diuretics produce?

A

Large volume of dilute urine

20
Q

What does the countercurrent multiplier achieve?

A

Generates a concentration gradient in the medullary intersistium

21
Q

What is the function of the vasa recta?

A

Delivers O2 to the medulla

Removes volume from the interstitium

22
Q

What is the flow rate in the vasa recta like?

A

Low, allows the equilibrium of interstitium

23
Q

Where is ADH produced?

A

Posterior pituitary

24
Q

What does ADH do at the collecting duct?

A

Increases water reabsorption

Urinary (17 decks)

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