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Urinary > Glomerular filtration > Flashcards

Glomerular filtration Flashcards

1
Q

What is the GFR/ day?

A

180L/day

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2
Q

What are the basic renal processes?

A

Filtration
Reabsorption
Secretion

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3
Q

What % of CO do the kidneys receive?

A

20-25%

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4
Q

What is the GFR/min?

A

125ml/min

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5
Q

What forces favour filtration?

A

Hydrostatic pressure

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6
Q

Which forces favour reabsorption?

A

Oncotic pressure

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7
Q

Which molecules are filtered freely?

A

Na, K, Cl, h2O, Urea, Glucose

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8
Q

Which molecules in the plasma are not filtered at the glomerulus?

A

RBCs

Albumin

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9
Q

What is the structure of the afferent arteriole? Function?

A

Short & wide

Reduces resistance to flow

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10
Q

What is the structure of the efferent arteriole? Function?

A

Long & narrow

High post-capillary resistance

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11
Q

What process occurs at the glomerular capillaries? What force allows this?

A

Filtration

High hydrostatic pressure

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12
Q

What is the glomerular capillary pressure determined by?

A

The diameter of the afferent & efferent arterioles

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13
Q

What are the extrinsic factors which control the diameter of glomerular capillaries?

A

Sympathetic nerves
Circulating adrenalin
Angiotensin II

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14
Q

What will happen to the glomerular capillary pressure and GFR if afferent arteriole resistance increases?

A

Decreases

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15
Q

What will happen to PGc and GFR is efferent arterioles are constricted?

A

Increases

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16
Q

What does autoregulation allow the control of in the kidneys?

A

Intrinsic control of glomerular capillary pressure, maintaining BP & GFR

17
Q

What is the auto regulatory range that Mean Arterial Blood Pressure is maintained within? Advantages?

A

60-130mmHg

Maintains GFR over a range of BPs

18
Q

In what situations can auto regulation be over ridden?

A

Haemorrhage

19
Q

How much urine is excreted per day?

A

1-2L/day

20
Q

What is reabsorption driven by? Why? Where does this occur?

A

Oncotic pressure
High concentration of plasma proteins
Peritubular capillaries

21
Q

What % of water, glucose, Na & urea filtered at the glomerulus is reaborbed?
Where?

A 
99%
100%
99.5%
50%
Proximal convoluted tubule

Urinary (17 decks)

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