Long Term Regulation of Arterial Blood Pressure. Flashcards

1
Q

Kidneys (via control of blood volume): Important site of synthesis for several hormones including:

A

Renin, Erythropoietin, 1,25-dihydroxyvitamin D3 (calcitriol)

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2
Q

Renin

A

Na+ and H2O balance

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3
Q

Erythropoietin

A

Erythrocyte Formation

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4
Q

1,25-dihydroxyvitamin D3 (calcitriol)

A

Ca2+ homeostasis

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5
Q

Renin-Angiotensin-Aldosterone-Antidiuretic Hormone System

A

Angiotensinogen> Renin comes in> Angiotensin I> Converting Enzyme comes in> Angiotensin II> Stimulation of aldosterone secretion> Increased Preload (If Angiotensin II does not stimulate aldosterone, afterload is increased)

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6
Q

Location of Osmoreceptors

A

Hypothalamus and Macula Densa; Afferents for the Renin-Angiotensin-Aldosterone System

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7
Q

Hypothalamus Osmoreceptors

A

Plasma osm increases cause osmR>

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8
Q

Macula Densa Osmoreceptors

A

Cell cluster in Kidney (distal tubule); Affererently to Macula densa (Increase PGI); PGI signal juxtaglomerular apparatus (kidney): Increase Renin; RAAAS system now active

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