Locomotion 4 Flashcards
What is the CNS and PNS made up of
CNS = Central Nervous System = BRAIN & SPINAL CORD PNS = Peripheral Nervous System = NERVES & GANGLIA
What are nuclei and ganglia
1) Nuclei -> collection of neuronal cell bodies within the CNS
§ On the surface of the cerebrum and cerebellum (cerebral and cerebellar cortex), spinal cord (grey matter)
2) Ganglia -> collections of neuronal cell bodies outside the CNS
§ Peripheral ganglia
What are the 3 types of neurons and the percentage of total neurons
1) Sensory neuron - 15% are sensory
2) Interneuron - 80%
3) Motor neuron - 3% are effector neurons -> process attached to the glands or muscles to contract or secrete
What is grey and white matter
Grey matter
- Consists of neuron cell bodies and supporting cells (glia)
- Appears pinkish grey in fresh CNS material
- unmyelinated but still insulated my myelin
White matter
- Consists of networks of neuron cell processes and their supporting cells
- appears white because of the high content of myelin
- Majority of the nervous system
Spinal nerves what are they formed from at what level of the vertebrae and how named in cervical then thoracic region
- Each spinal nerve have dorsal and ventral branches, spinal nerves formed when dorsal and ventral roots joint at intervertebral foramen
Cervical
C1 = skull and C1 (cranial to C1)
HOWEVER C8 between C7 and T1 therefore C8 cranial to T1 and T1 is caudal to T1 (between T1 and T2)
From then on all spinal nerves are caudal to corresponding vertebrae
Where is the information coming from or going in the dorsal, ventral and intermediate horn of the spinal cord
Dorsal horn
- information coming within -> SENSORY NEURONS
- general somatic and visceral afferent (sensory) -> muscle and glands
Ventral horn
- information going out of the spin - MOTOR NEURONS
- general somatic efferent - voluntary muscle movement
Intermediate horn
- INTERNEURONS generally general visceral efferent (glands and organ control)
- not present in cervical spinal
How many spinal nerves are within the dog in each region: Cervical, thoracic, lumbar, sacral and caudal and overall
cervical - 8 pairs thoracic - 13 pairs lumbar - 7 pairs sacral - 3 pairs caudal - variable Overall general 36 pairs
location of the cerebral hemispheres, cerebellum and brain stem within the brain
Cerebral hemisphers - dorsally and rostrally
Cerebellum - dorsally and caudally
Brain stem - central, ventral and caudal part of the brain
Somatic and autonomic nervous systems what convey impulses to
Somatic - skeletal muscle - voluntary movement
Autonomic - smooth muscle of viscera, blood vessels, cardiac muscles and glands
where are the origins within the spinal cord for parasympathetic and sympathetic nerves
Parasympathetic nerves have a cranial or sacral origin
Sympathetic nerves have a thoracic or lumbar origin and accompany the blood vessel to all parts of the body
What are the meninges and why does it consist of
- The connective tissue membranes which cover the brain and spinal
Consists of - dura mater, arachnoid mater and pia mater (external to internal)
- epidural space: external to the dura mater and contains fat and the vertebral venous plexi
○ Obliterated in the med cervical region CS (C2, C4) by fusion of the dura with the periosteum
Dura Matter other name, what is it and function
Pachymeninx)
- Dense, tough fibrous covering
- Encloses the spinal roots as they leave the spinal cord and fuses with the epineurium at the intervertebral foramen
Arachnoid Matter what is the other name, structure, where run and structures wtihin
Leptomeninges)
- Thin/delicate
- Just medial to the dura mater
1) subarachnoid space lies between the arachnoid and pia mater and contains cerebrospinal fluid (CSF)
2) arachnoid trabeculae are fine meningeal filaments that cross the arachnoid space between the arachnoid mater and the pia mater
What is the function of the cerebrospinal fluid
○ Cerebrospinal fluid maintained at positive pressure compared to blood pressure -> functions as a fluid cushion that helps the central nervous system
Pia Mater what is the other name, structure, function and ligament within
- Very delicate membrane which is fused to and closely follows the contours of the CNS, makes up the blood brain barrier
- Denticulate ligaments form on the lateral aspect of the spinal cord between the arachnoid and pia mater half way between succeeding spinal nerves
Ligaments help to suspend and stabilise the spinal cord in the vertebral canal
What is the main artery that runs through the veterbral canal and what does it supply
Ventral longitudinal artery -> the main artery
○ Good blood supply including intercostal arteries
○ In the neck the vertebral artery supplies the spinal cord through branches into intervertebral spaces of each vertebrae as runs up towards the head
What cervical vertebrae articulates with part of a rub and where
- 7th cervical vertebrae has caudal costal fovea which articulate with the cranial part of the heads of the first pair of ribs
Intervertebral disc where located and function
- Located between every vertebra expect between
○ Skull and C1
○ C1 and C2
○ The sacral vertebrae
Function: to unite the vertebrae and allow some movement between them - Thickest in the cervical and lumbar regions (especially lumbosacral joint)
What are the 2 areas of the intervertbral disc and structure, which way do discs general prolapse and why
1) Annulus fibrosus
- which is a thick fibrous outer ring with fibres running obliquely between vertebrae
- Thicker ventrally so more discs prolapse dorsally than ventrally in degenerative joint disease
2) Nucleus pulposus
- An amorphous gelatinous centre to the disc (thus allowing some “give” in all directions
- Remnant of the notochord
The presence of what in the thoracic region leads to disc rupture in thoracic region being rare
The presence of the intercapital ligament
List the 6 ligaments of the spinal column
1) interspinous
2) yellow (ligamentum flava)
3) nuchal
4) supraspinous
5) ventral longitudinal
6) dorsal longitudinal
Interspinous ligament where present and function
- Connect adjacent vertebral spines
- May blend dorsally with the supraspinous ligaments and laterally with the interspinalis muscles
Yellow ligament what also called, where located and function
(Ligamentum flava)
- Loose thin elastic sheets between the arches of adjacent vertebrae
- Laterally they blend with the articular capsules surrounding the articular processes
Epidural space is medial to the yellow ligaments
Nuchal ligament structure and where present
- Longitudinal yellow, elastic fibres with attach cranially to the caudal part of the spinous process of C2 and attaches caudally to the dorsal tip of the dorsal spinal process of T1
Supraspinous ligament where present and function
- Heavy bands that extends from T1 to C3 attaching to the dorsal spinous processes
- More important for preventing separation of the spinous processes during flexion of the vertebral column than are the Interspinous ligaments
Ventral and dorsal longitudinal ligaments where present
Ventral longitudinal ligament
- Lies on the ventral aspect of the vertebral bodies from the axis to the sacrum and is best developed in the caudal thorax
Dorsal longitudinal ligaments
- Lies along the dorsal aspect of the vertebral bodies (floor of the spinal canal)
- Extends from the dens of the atlas to the end of the vertebral canal in the caudal vertebrae
Atlantoaxial articulation how does this occur and held in place
- a pivot joint between the atlas and the axis that allows the head to rotate around the longitudinal axis
- the dens is a peg of bone running from cranial C2 onto the floor of the spinal canal of C1
○ held in place by the apical ligament of the dens (x3) and the transverse atlantal ligament
What are the synovial joints within the vertebrae for the cervical and thoracic
- 4 synovial joints within the vertebrae -> 2 cranial (cranial articular surfaces) and 2 caudal (caudal articular surfaces)
- More with the thoracic - ribs - 6 MORE as 3 on each side therefore has 10 SYNOVIAL JOINTS
○ Ribs articulation within the head between
i. cranial vertebrae and caudal costal fovea
ii. caudal vertebrae to the cranial costal fovea
○ Ribs articular within the tubercle between
i. caudal vertebrae to the transverse process
What is the white matter within the spinal cord divided into and what are they associated with
3 paired funiculi
- Dorsal funiculus associated with ascending proprioceptive function - SENSORY FUNCTION
- Lateral funiculus facilitates flexor function - MOTOR FUNCTION
- Ventral funiculus facilitates extensor function - MOTOR FUNCTION
What are the 3 structures at the end of the spinal cord and the extent of the spinal cord in dogs, cat, and horses
- conus medullaris is the tapered caudal end of the spinal cord.
- cauda equina is the nerve roots coming off the conus medullaris or the nerve roots and the conus medullaris
- filum terminale is the very terminal portion of the spinal cord tissue which is formed by ependymal and glial cells
○ Dog L6 or L7
○ Cats L7
○ Horse S2
List the 6 anatomical division of the spinal cord, describe and how best seen
1) dorsal median septum is found in the dorsal midline
2) ventral median fissure is the cleft in the ventral midline
3) dorsolateral sulcus - where the dorsal roots enter the cord
4) ventrolateral sulcus (usually indistinct) - where the ventral roots enter the cord
5) small central canal lined with ependyma and filled with CSF - a remnant of the neural canal
6) sulcus limitans a longitudinal groove on the lateral wall of the spinal cord which divides the alar and basal plates.
Visualisation of these structures is best seen under low power magnification
What are the Lower motor neurons and upper motor neurons and their function
1) Lower motor neurons (LMN)
- Efferent neurons connecting the CNS with the target organ
- Go straight to the motor end plate
2) Upper motor neurons (UMN)
- Efferent neurons within the CNS that influence (mostly inhibit) activity of the LMN
- Contained entirely within the CNS however if in spinal cords within the lateral and ventral horns
What results from with dysfunction of LMN and UMN
LMN - hyporeflexia, atonia, neurogenic atrophy (acute and severe)
UMN - hyperreflexia and hypertonia due to loss of descending inhibitory influence on LMNs
What tracts are found in the peripheral and central location within the spinal cord
PERIPHERAL LOCATION = ascending and long tract
- More likely to be damaged as longer and superficial
CENTRAL LOCATION - descending and short tracts
What tracts are found within the dorsal, lateral and ventral funiculi (ascending or descending and what muscles act on)
Dorsal funiculi - primarily contains ascending proprioceptive tracts
1. Hindlimb tracts -> dorsal and central
2. Forelimb tracts -> deeper and more lateral
Lateral funiculi - ascending and descending tracts
- Descending tracts generally facilitate flexors
Ventral funiculi - descending tracts
- Descending tracts generally facilitate extensors
What does one spinal nerve divide into and what does this supply
1) Dorsal branch - supplies the epaxial muscle and skin
2) Ventral branch - supplying the hypaxial muscle and skin
3) Ramus communicans - only in thoracic and cranial lumbar regions