Local Anesthesia Flashcards
What is local anesthesia?
Loss of pain sensation and movement in an area of the body due to blockage of nerve conduction
What is the mechanism of action for local anesthesia?
interferes with movement of sodium ions across neuronal cell membranes
What are the indications for using local anesthesia? (4)
- Minor surgical procedures
- Large animals
- Suturing a wound, cleaning a wound
- Doesn’t usually work well for cats
What are the 2 types of local anesthetics?
- Esters
2. Amides
What are examples of Esters? (4)
- Cocaine
- Procaine
- Chlorprocaine
- Proparacaine
What are the characteristics of Esters? (2)
- short-acting effects
2. apply topically to mucous membranes
What are the examples of Amides? (3)
- Lidocaine
- Mepivacaine
- Bupivacaine
Characteristics of Lidocaine (3)
- 1.5 - 2 hours
- Faster effect
- Least potent
Characteristics of Mepivacaine (2)
- less irritating to tissues
2. 1.5-3 hours
Characteristics of Bupivacaine (3)
- 15-30 min to take effect
- lasts 4-6 hours
- most potent
Characteristics of Amides (2)
- Longer lasting effects
2. topical or injection
What are the possible adverse effects of using local anesthetics? (5)
- Tissue irritation
- Allergic reaction
- Nerve trauma
- Respiratory paralysis, sympathetic bockade w/ epidural injections
- Systemic toxicity
What are the effects of systemic toxicity? (4)
- muscle twitching
- hyperexcitability
- seizures
- goats, sheep, cats are more sensitive
How do you use a topical local anesthetic? (2)
- Put on an open wound to numb/desensitize
2. Glottis opening for cats to intubate
What are the 2 localized infiltration anesthetics?
- line block
2. nerve block