local anaesthetic Flashcards
what axons are most susceptible to local anaesthetic and what do they do
a - delta - mechano , thermo (cold), nociception, chemoreception
c fibres - mechano, thermo (hot), nociception
a - beta - mechano
a - alpha - proprioception
in what form is local anaesthetic active
partly dissosciated (B.HCl) can only pass through membrane in unionised form (B + H + Cl)
why do local anaesthetic preparations contain vasoconstrictors
most LAs are vasodilators and this increased blood flow will wash away the LA therefore decreasing the duration of action
vasoconstrictors include adrenaline and felypressin
what do vasoconstrictors work on and what do they do
adrenoreceptors
alpha receptors - vasoconstriction
beta 1 receptors - increase HR
beta 2 receptors - vasodilation
common composition of lignocaine
2% lignocaine HCl with 1:80000 adrenaline
what does 3% prilocaine mean
3g per 100ml
benefits of using vasoconstrictor
longer duration
less LA in bloodstream to kept to a localised area
aids haemostatic control
symptoms of allergic reaction
red itchy rash , red itchy eyes, runny nose, sneezing, wheezy, coughing
symptoms of anaphylaxis
breathing difficulties, tachycardia, faint , confusion, collapse
where is LA deposited during an infiltration technique
terminal end branches
where is LA deposited during a block technique
beside nerve trunk
bevel
tip of needle
hub
base of needle, most prone to fracture
is the LA cartridge inserted into the open end of the needle with the gold end or the clear end towards the needle
gold end
clear end has the wee gap for the twist safety mechanism
method of assembling an ultra safety plus twist
1 - insert LA cartridge into open end of needle with gold end towards needle
2 - attach handle and do the safety twist
3 - pull needle safety cover and ensure is covers safety lock
4 - remove needle sheath
gauge number
tells us size of needle lumen
smaller gauge number = larger lumen e.g 30 gauge needle has smaller lumen than 25 gauge