Liver Abscesses and Cysts Flashcards

1
Q

Define Liver Abscess?

A

Liver infection resulting in a walled off collection of pus

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2
Q

Define Liver Cyst?

A

Liver infection resulting in a walled off collection of cyst fluid

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3
Q

What is the aetiology of Liver abscesses and cysts?

A

Pyogenic (producing pus)
Amoebic Abscess
Hyatid Cyst
Other causes: TB

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4
Q

What are the Pyogenic causes of Liver Absecesses and Cysts?

A
Escherichia coli
Klebsiella 
Enterococcus 
Bacteriodes 
Streptococci
Staphylococci 
60% are caused by biliary tract disease
15% have unknown cause
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5
Q

What are some examples of Biliary Tract Disease?

A

Gallstones
Strictures
Congenital Cysts

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6
Q

What are Amoebic Abscesses caused by?

A

Entamoeba Histolytica

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7
Q

What is Hydatid Cyst caused by?

A

Caused by tapeworm Echinococcus granulosis

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8
Q

What is a Hyatid?

A

A cyst containing watery fluid

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9
Q

What is the epidemiology of Liver Absecesses and Cysts?

A

Pyogenic is the most common type of liver abscess in the industrialised world
Amoebic liver abscess - most common worldwide
Hydatid Cysts - common in sheep-rearing countries

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10
Q

What are the presenting symptoms of Liver Absecesses and Cysts?

A
Fever 
Malaise 
Nausea 
Anorexia 
Night Sweats 
Weight Loss 
RUQ/epigastric pain that may be referred to the shoulder (due to irritation of the diaphragm)
Jaundice 
Diarrhoea 
Pyrexia of unknown origin
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11
Q

What do you ask about in the history for Liver Absecesses and Cysts?

A

Make sure you ask about foreign travel

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12
Q

What are the signs of Liver Absecesses and Cysts?

A
Fever - continous or spiking 
Jaundice 
Tender hepatomegaly (right lobe affected more than left)
Right lung base:
- Dullness to percussion
- Reduced Breath Sounds 
- Due to reactive pleural effusion
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13
Q

What bloods do we do to invesigate Liver Absecesses and Cysts?

A
FBC 
LFTs
High ESR and CRP 
Blood Cultures 
Amoebic and hydatid serology
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14
Q

What do we look for on a FBC for Liver Absecesses and Cysts?

A

Mild anaemia
Leukocytosis
High eosinophils (if hydatid disease)

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15
Q

What do we look for on LFTs for Liver Absecesses and Cysts?

A

High ALP

High bilirubin

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16
Q

Why do we do a Stool MC&S for Liver Absecesses and Cysts?

A

For E.histolytica

17
Q

Why do we do a Liver US or CT/MRI for Liver Absecesses and Cysts?

A

Helps localise structure of mass

18
Q

Why do we do a CXR for Liver Absecesses and Cysts?

A

Check for right pleural effusion or atelectasis, raised hemidiaphragm

19
Q

Why do we need to do Aspiration and culture of the abscess material?

A

Most pyogenic liver abscesses are polymicrobial

Amoebic abscesses have fluid of necrotic hepatocytes and trophozoites