Gastrointestinal Perforation Flashcards

1
Q

Define Gastrointestinal Perforation?

A

Perforation of the wall of the GI tract with spillahe of bowel contents

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2
Q

What is the aetiology of Large Bowel perforation?

A

COMMON:

  • Diverticulitis
  • Colorectal Cancer
  • Appendicitis

Others: volvulus, UC (toxic megacolon)

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3
Q

What is the aetiology of Gastroduodenal perforation?

A

COMMON:
Perforated duodenal or gastric ulcer
Others: gastric cancer

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4
Q

What is the aetiology of Small Bowel perforation (RARE)?

A

Trauma
Infection (E.g. TB)
Crohn’s Disease

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5
Q

What is the Oesophageal cause of Gastrointestinal Perforation?

A

Boerhaave’s perforation - rupture of the oesophagus following forceful vomiting

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6
Q

What are the risk factors of Gastrointestinal Perforation?

A

Risk factors of cause (e.g. gastroduodenal - NSAIDs, steroids, bisphosphonates)

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7
Q

What is the epidemiology of Gastrointestinal Perforation?

A

Incidence depends on cause

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8
Q

What are the presenting symptoms of Gastrointestinal Perforationbased on?

A

Depends on CAUSE

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9
Q

What are the presenting symptoms of Large Bowel perforation?

A

Peritonitic abdominal pain

IMPORTANT: make sure you rule out ruptured AAA

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10
Q

What are the presenting symptoms of Gastroduodenal perforation?

A

Sudden-onset severe epigastric pain - worse on movement
Pain becomes generalised
Gastric malignancy - may have accompanying weight loss and nausea/vomiting

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11
Q

What are the presenting symptoms of Oesophageal perforation?

A

Severe pain following an episode of violent vomiting

Neck/chest pain and dysphagia develop soon afterwards

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12
Q

What are the signs of Gastrointestinal Perforation on clinical examination?

A
Very unwell
Signs of shock
Pyrexia
Pallor 
Dehydration
Signs of peritonitis 
Loss of liver dullness (due to overlying gas)
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13
Q

What are the signs of peritonitis on clinical examination?

A

Guarding
Rigidity
Rebound tenderness
Absent bowel sounds

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14
Q

What bloods do you do for Gastrointestinal Perforation?

A

FBC
U&E
LFTs
Amylase

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15
Q

Why do we do Amylase for Gastrointestinal Perforation?

A

Will be reaised with perforation (but shouldn’t be astronomical (as seen in pancreatitis))

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16
Q

Why do we do an Erect CXR for Gastrointestinal Perforation?

A

Shows air under the diaphragm

17
Q

Why do we do an AXR for Gastrointestinal Perforation?

A

Shows abnormal gas shadowing

18
Q

Why do we do a Gastrograffin Swallow for Gastrointestinal Perforation?

A

For suspected oesophageal perforations

19
Q

What is the general management plan for Gastrointestinal Perforation?

A
Correct fluid and electrolytes 
IV antibiotics (with anaerobic cover)
20
Q

What is the surgical management plan for Large Bowel perforation?

A

Identify site of perforation
Peritoneal lavage
Resection of perforated section (usually as part of a Hartmann’s procedure)

21
Q

What is the surgical management plan for Gastroduodenal perforation?

A

Laparotomy
Peritoneal Lavage
Perforation is closed with an omental patch
Gastric ulcers are biopsied
H. Pylori eradication if positive for H.Pylori

22
Q

What is the surgical management plan for oesophageal perforation?

A

Pleural lavage

Repair of ruptured oesophagus

23
Q

What are the complications of Large and Small bowel perforation?

A

Peritonitis

24
Q

What are the complications of Oesophageal Perforation?

A

Mediastinitis, shock, overwhelming sepsis and death

25
Q

What is the prognosis for patients with gastroduodenal perforation?

A

Gastric ulcers have higher morbidity and mortality than duodenal ulcers
Poor prognosis for perforated gastric carcinomas

26
Q

What is the prognosis for patients with Large Bowel perforation?

A

High risk of faecal peritonitis if left untreated

This can lead to death from septicaemia and multiorgan failure