Irritable Bowel Syndrome Flashcards

1
Q

Define Irritable Bowel Syndrome (IBS)?

A

A functional bowel disorder defined as recurrent episodes of abdominal pain/discomfort (in the absence of detectable organic pathology) for > 6 months of the previous year, associated with two of the following:

  • Altered stool passage
  • Abdominal bloating
  • Symptoms made worse by eating
  • Passage of mucous
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2
Q

What are some of the causes of IBS?

A

Visceral sensory abnormalities
Gut motility abnormalities
Psychosocial factors (e.g. stress)
Food intolerance (e.g. lactose)

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3
Q

What is the epidemiology of IBS?

A

Common
10-20% of adults
More common in females (2:1 ratio)

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4
Q

What are the presenting symptoms of IBS?

A
6+ month history of abdominal pain
Altered bowel frequency (> 3 motions per day or < 3 motions per week)
Abdominal bloating 
Change in stool consistency 
Passage with urgency or straining 
Tenesmus
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5
Q

What is the character of the abdominal pain in IBS?

A

Pain if often colicky
It is in the lower abdomen
Relieved by defecation or passing of flatus

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6
Q

What are the red flag symptoms of IBS?

A

Weight Loss
Anaemia
PR bleeding
Late onset (> 60 yrs)

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7
Q

What do you do if any of the red flag symptoms are present in IBS?

A

Exclude colonic malignancy

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8
Q

What are the signs of IBS on physical examination?

A

Usually normal on examination

Sometimes the abdomen may appear distended and be mildly tender on palpation on one or both iliac fossae

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9
Q

What is diagnosis generally made from in IBS?

A

The history but organic pathology must be excluded

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10
Q

What bloods do we do for IBS?

A
FBC (anaemia)
LFT
ESR
CRP
TFT
anti-endomysial/anti-transglutaminase antibodies (coeliac disease)
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11
Q

Why do we do a Stool examination for IBS?

A

Microscopy and culture for infective cause

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12
Q

Why do we do an US for IBS?

A

Exclude gallstone disease

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13
Q

Why do we do a Urease breath test for IBS?

A

To exclude dyspepsia due to H.pylori

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14
Q

When do we do an Endoscopy for IBS?

A

If other pathologies are suspected

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15
Q

What advice do you give someone with IBS?

A

Dietary modification

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16
Q

What does the medical management plan for IBS depend on?

A

Main symptoms affecting the patient

17
Q

What is the medical management plan for IBS?

A

Antispasmodics (e.g. buscopan)
Prokinetic agents (e.g. domperidone, metaclopramide)
Anti-diarrhoeals (e.g. loperamide)
Laxatives (e.g. senna, movicol, lactulose)
Low-dose tricyclic antidepressants (may reduce visceral awareness)

18
Q

What is the psychological therapy for IBS?

A

CBT

Relaxation and psychotherapy

19
Q

What are the possible complications of IBS?

A

Physical and psychological morbidity

Increased incidence of colonic diverticulosis

20
Q

What is the prognosis for patients with IBS?

A

Chronic relapsing and remitting course of disease

Often exacerbated by psychosocial stresses