Liver Flashcards

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1
Q

Vessels into the liver

A

Hepatic artery

Hepatic portal vein (from digestive system)

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2
Q

Vessels out of the liver

A

Hepatic vein

Bike duct

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3
Q

Cells within the liver

A

Hepatocytes

Kupffer cells

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4
Q

Liver structure

A

Lobes divided into lobules (which are cylindrical)

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5
Q

Division of vessels within the liver

A

Hepatic artery and hepatic portal vein run parallel to the lobules
- Called Inter-lobular vessels
Blood is mixed in the sinusoid

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6
Q

Which chamber is blood mixed in

A

Sinusoid

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7
Q

Function of Kupfer cells

A

Breakdown and recycle old reed blood cells

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8
Q

Which vessel does blood drain into after the sinusoid

A

Branch of hepatic vein

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9
Q

How is bile produced

A

Bile is produced against the flow of blood in a different vessel (bile canaliculus)
Flows into the branch of the bile duct

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10
Q

Function of the liver

A

Storage of glycogen

Detoxification

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11
Q

Detoxification of alcohol

A

Ethanol - 2H+ -> Ethanal by reducing NAD (ethanol dehydrogenase)
Ethanal - 2H+ -> Ethanoic acid by reducing NAD (ethanal dehydrogenase)
Ethanoic acid + CoA -> Acetyl CoA

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12
Q

Formation of urea

A

Amino acid -> Ammonia + keto acid (deamination)

Ammonia -> Urea (ornithine cycle)

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13
Q

Deamination

A

Amino acid + 1/2O2 makes Keto acid + NH3

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14
Q

Ornithine cycle

A

Ornithine + NH3 + CO2 -> Citrulline + H2O
Citrulline + NH3 -> Aginine + H2O
Aginine + H2O -> Urea + Ornithine

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