Liver. 1. Flashcards

1
Q

What can be diagnosed on FNA on the liver?

A

Round cell neoplasia.

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2
Q

What can be diagnosed with a cholecystocentesis?

A

Bacterial cholangitis.

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3
Q

What can only be diagnosed with a liver biopsy?

A

Copper storage hepatopathy.

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4
Q

You want to diagnose pancreatitis.

Whats most reliable diagnostic tool?

A

CPLI.

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5
Q

Which part of the liver is the functional unit?

A

Acinus.

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6
Q

What is the blood flow through the liver?

A

Hepatic artery and portal vein (afferent).

Acinus, central vein, hepatic vein (efferent).

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7
Q

Can you diagnose the cause of end-stage liver?

A

No. Everything will be fibrotic and you can’t tell what happened.

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8
Q
  1. What liver cells make bile?
A

Hepatocyte.

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9
Q
  1. Where is bile stored?
A

Bile caniculi.

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10
Q

Can liver enzymes be normal or even low with liver damage?

A

Yes, when the cells become too damaged to produce enzymes.

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11
Q

What are the minimum coagulation tests to run for liver issues?

A

PT and aPTT.

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12
Q

Where does cholecystokinin come from?

A

Intestinal cells.

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13
Q

What does cholecystokinin do?

A

Stimulates gallbladder contraction.

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14
Q

What is the afferent blood supply to the liver?

A

Hepatic artery.

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15
Q

What enzymes are elevated with liver injury?

A

ALT, SDH, AST (not GGT, ALP).

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16
Q

A 10-year Dog presents with multiple porto-systemic shunts (PSS).

What do you do and what is the prognosis?

A

Euthanize; grave prognosis.

17
Q

What are the top 4 differential diagnoses in an icteric cat?

A

Hepatolipidosis.

Cholangitis/cholangiohepatitis.

FIP.

Lymphoma.

18
Q

Do you check bile acids on an animal with jaindice?

A

No.

19
Q

What are the 3 components of triaditis?

A

Duodenal lesions.

Biliary tract lesions.

Pancreatic lesions.

20
Q

What liver enzymes are increased in cholangitis?

A

All liver enzymes including GGT.

21
Q

What is is a good drug for hepatobiliary disease?

A

Ursodiol.

22
Q

What drug won’t reverse cirrhosis but will prevent it?

A

Ursodiol.

23
Q

What characterises suppurative cholangitis?

A

Neutrophilic infiltrates.

24
Q

What characterises non-suppurative cholangitis?

A

Lymphoplasmacytic infiltrates

it may progress to the suppurative form.

25
Q

What kind of hepatic neoplasia is less common in the cat?

A

Primary neoplasia.

Metastatic is more common.

26
Q

What is used to diagnose an extrahepatic bile duct obstruction?

A

Ultrasound.

27
Q

What shunt is the most common in cats and small dogs?

A

Single extrahepatic shunt.

28
Q

What indicates a PSS in a cat?

A

Dramatically increased bile acids, above 100.

29
Q

What must be stabilised prior to PSS surgery in a cat?

A

Hepatic encephalopathy.

30
Q

What is the most common liver disease in cats?

A

Idiopathic/primary hepatolipidosis.

31
Q

What liver values increase in idiopathic/primary hepatolipidosis?

A

All liver values, but GGT remains normal.

32
Q

What 3 signs are pathognomonic for idiopathic/primary hepatolipidosis?

A

Ventroflexion of the neck due to hypokalemia.

Hypophosphatemia.

Thiamine deficiency.

33
Q

What is the best treatment for idiopathic/primary hepatolipidosis?

A

Prolonged aggressive nutritional therapy.