lithium Flashcards

1
Q

what

A

mood stabiliser

used for bipolar disorder

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2
Q

therapeutic range

A

0.4-1 mmol/L

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3
Q

side effects

A
fine tremor
dry mouth 
GI upset
increased thirst 
inc urination 
hypothyroidism 
hyperparathyroidism 
nephrotoxicity
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4
Q

Monitoring - when should lithium levels be checked

A
12hrs post dose
one week after starting treatment 
one week after dose change 
weekly until levels stable 
3 monthly once levels stable
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5
Q

what should be monitored every 6mo

A

BMI
U&Es, eGFR
calcium
TFTs

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6
Q

clinical features of lithium toxicity

A
coarse tremor
seizure
lack coordination
dysarthria 
arrythmias
visual disturbance
hyperreflexia
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7
Q

lithium toxicity - what serum levels

A

1.5mmol and above

severe if ~2+

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8
Q

ECG changes

A

T wave flattening/inversion

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