benzodiazepines Flashcards
1
Q
uses
A
sedation hypnotic anxiolytic anticonvulsant muscle relaxant
2
Q
withdrawing benzodizepines
A
withdrawn in steps of ~1/8 of daily dose every 14days
3
Q
suggested protocol for withdrawal
A
- switch pt to equivalent dose of diazepam
- reduce dose diazepem by 2/2.5mg every 2-3wks
4
Q
benzodiazepine MOA
A
enhance effect of inhibitory GABA by increasing frequency of chloride channels
5
Q
barbituates MOA
A
enhance effect inhibitory GABA by increasing duration of chloride channel opening