benzodiazepines Flashcards

1
Q

uses

A
sedation 
hypnotic 
anxiolytic 
anticonvulsant 
muscle relaxant
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2
Q

withdrawing benzodizepines

A

withdrawn in steps of ~1/8 of daily dose every 14days

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3
Q

suggested protocol for withdrawal

A
  • switch pt to equivalent dose of diazepam

- reduce dose diazepem by 2/2.5mg every 2-3wks

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4
Q

benzodiazepine MOA

A

enhance effect of inhibitory GABA by increasing frequency of chloride channels

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5
Q

barbituates MOA

A

enhance effect inhibitory GABA by increasing duration of chloride channel opening

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