LISTERIA Flashcards
Coccobacillary in form and are arranged singly
or in short chains that resemble streptococci
LISTERIA
small, smooth, translucent, grayishblue and are surrounded by a narrow zone of bhemolys
Culture of Listeria
• Both human and animal pathogens
• Aerobic or facultatively anaerobic and non-spore
forming
LISTERIA MONOCYTOGENES
- Grow high salt medium with up to 10% NaCl
- Optimal growth: 30C to 37C but can grow at 4C
(cold temp)
LISTERIA MONOCYTOGENES
- Recovered from the soil, dust, water, dairy
products and processed meats - Causes miscarriage or stillbirth in humans
LISTERIA MONOCYTOGENES
o Listeriolysin O (hemolytic and cytotoxic)
o Catalase,
o Superoxide dismutase (SOD),
o Phospholipase C and
o p60 (surface protein)
VF of Listeria Monocytogenes
ingestion of contaminated food such as
meat, chicken, dairy products and vegetables.
MOA of Listeria Monocytogenes
Infection caused by Listeria
Listeriosis
Infected pregnant women may pass the
organisms onto the fetus
Listeriosis
- Infection affects neonates, pregnant women and
immunocompromised.
Listeriosis
Meat products should be thoroughly cooked or
heated before consumption
Listeriosis
After ingesting contaminated dairy products like
cheese
Listeriosis
o During 3rdtrimester of pregnancy
o Miscarriage or stillbirth
o S/Sx: Flu-like illness, fever, myalgia
Maternal Disease (Pregnancy)
o Associated with an intrauterine infection
due to the aspiration of infected amniotic
fluid
o Infected infants are at full term and
appear healthy at birth.
o Lead to meningitis that is usually seen in
3rd week of life
Neonatal Disease
Develops through the ingestion of
contaminated dairy products and
processed meat products.
Disease Of Immunocompromised
