Lipolysis (TG Mobilization)

Question 1

What is Lipolysis?

Answer 1

TG’s broken down for fuel or local storage from adipose

Question 2

Lipolysis can do what simultaneously?

Answer 2

Synthesize & Desynthesize TG’s

Question 3

Where does TG mobilization occur?

Answer 3

Adipose, Muscle (IMTG), Blood Supply

Question 4

What is a Triglyceride?

Answer 4

Glycerol + 3 FA’s

Question 5

What molecule is required for TG breakdown and what is the process called?

Answer 5

H20 / Hydrolysis

Question 6

What activates Lipolysis?

Answer 6

Low Insulin
Low Glucose
Exercise (Ca2++)
Epi/NE (AMP)

Question 7

What is the activation cascade for PKA?

Answer 7

Exercise Contractions (Ca2++) or Epi/NE (AMP) activate PKA which triggers HSL + Phosphorylation

Question 8

When Glycerol is released from FA’s during TG breakdown, where is it taken up by & why?

Answer 8

Liver for GNG

Question 9

What enzyme phosphorylates glycerol to produce G3P for GNG pathway + TG Synthesis

Answer 9

Glycerol Kinase

Question 10

What enzyme converts FFA into Fatty Acel CoA for step 1 of TG Synthesis?

Answer 10

Acel CoA Synthase