Lipids Flashcards
structural lipids
-component of phospholipid bilayer, protects cell from environment
phospholipids
-hydrophilic polar head with a hydrophobic fatty acid tail
saturated fatty acid tail
-only single bonds, more stable/form solids at room temp
unsaturated fatty acid tail
- one or more double bonds, create kinks
- liquid at room temp
glycerophospholipid
- contains a glycerol backbone
- important in membrane synthesis
sphingolipids
- sphingosine backbone and long, np fatty acid tails and polar head
- ex: antigens on RBCs
waxes
- consist of esters of long chain fatty acids with long chain alcohols
- form malleable solids and protect against environment
signaling lipids
- intracellular messengers, hormones
- steroids, prostaglandins, and fat-soluble vitamins
steroids
- 4 cycloalkane rings fused together, non polar
- ex: cholesterol
cholesterol
- major component of the phospholipid bilayer and helps maintain fluidity (amphipathic)
- stabilize cell membrane against temp changes
- high temps: keeps it from being too permeable
- low temps: keeps it from solidifying
hypercholesterolemia
- high cholesterol
- accumulation of cholesterol on the walls of the arteries lead to atherosclerosis
prostaglandins
- 20 C molecules that are unsaturated carboxylic acids, contain a 5 C ring
- regulates synthesis of cAMP
lipid (fat)-soluble vitamins
- must be consumed in diet
- fat-soluble vitamins can accumulate in stored fat
- ex: vitamin A, D, E, K
vitamin A
- unsaturated hydrocarbon with roles in vision, growth/development, and immune function
- retinal
vitamin D
- aka cholecalciferol
- convert to calcitriol which increase calcium and phosphate uptake in the intestines and decreases excretion of Ca in the kidneys
- promotes bone production
vitamin E
- lipids with a substituted hydrophobic aromatic ring
- prevents oxidative damage
vitamin K
-vital to formation of prothrombin, an important clotting factor
triacylglycerols
-lipids for energy storage b/c they are light-weight and energy rich
triglycerides
-3 fatty acids bound to a glycerol, nonpolar
saponification
hydrolysis of triglycerides using a strong base (soaps)