Lipids 3

Question 1

RDS is characterized by what type of ratio?

Answer 1

lecithin/sphingolmyelin ratio of 1.8

Question 2

What are phospholipids made up of?

Answer 2

2 fa’s and a phosphate containing head group on glycerol

Question 3

What are plasmologens made up of?

Answer 3

1 fa
1 fatty alcohol
polar head group on glycerol

Question 4

Spingolipids are made up of?

Answer 4

1 FA
1 polar head group on sphingosine

(NO GLYCEROL)

Question 5

What do spingolipids NOT contain?

Answer 5

no glycerol

Question 6

How do we make phosphatidylcholine simply?

Answer 6

you take an CTP and phosphocoline and activate it to CDP-choline and DAG.. and then you make PC and CMP

Question 7

What is a biologically important lipid of the innter mitochondrial membrane?

Answer 7

cardiolipin

Question 8

Describe the asymmetry of the lipid bilayers.

Answer 8

outer leaflet: rich in PC and sphingomyelin

2. inner leaflet: rich in PE and - changed lipids such as PS