Carb Metabolism 2 Flashcards
RBCs rely exclusively on what for energy?
glycolysis because they DO NOT HAVE MITOCHONDRIA
All the steps of glycolysis :)
:)
What enzyme do we use to convert Glyceraldehyde 3 phosphate + NAD –> 1,3 bisphosphoglycerate?
glyceraldehyde phosphate dehydrogenase
What enzyme do we use yo convert 1,3 bisphosphoglycerate + ADP –> 3 phosphoglycerate
phosphoglycerate kinase
What are the 3 irreversible steps of glycolysis?
- Glucose + ATP –> hexokinase –> glu 6 phosphate
- Fruc 6 P + ATP –> PFK 1 –> Fruc 1,6 bisphosphate
- PEP + ADP –> pyruvate kinase–> pyruvate + ATP
Fructose can be used in two different ways (in 2 different areas..) explain
LIVER: Fructose –> fructokinase –> fructose 1 p
Fructose 1 p –> aldolase B –> Glyceraldehyde + DHAP (DHAP GOES TO GLYCOLYSIS)
MUSCLE: Fructose –> hexokinase –> fructose 6 P –> Glycolysis
Hexokinase is found where?
muscle
Fructokinase is found where?
liver
What does Galactose ultimately get broken down into?
Glucose 6 phosphate
How do we take UDP-glucose and get it to glucose 1 p? (1 step)
UDP-glucose –> Glu 1 P uridyltransferase–> glucose 1 p
What results from a deficiency of liver fructokinase?
essential fructosuria
Is essential fructosuria harmful?
no, fructose does not get converted to fruc 1 P and will be excreted in the urine
What is hereditary fructose intolerance?
aldolase B defiency, resulting in buildup of fruc 1 P; this can be bad for the liver
What happens if aldolase B is deficient?
hereditary fructose intolernance
How do you treat hereditary fructose intolerance?
fructose-free diet