Carb Metabolism 4 Flashcards
Where does glycogen synthesis occur?
liver and muscle
Glucose 6 P —> ? –> gluc 1 p?
phosphoglucomutase
glu 1 P –> ? –> UDP glucose?
UDP-glucose pyrophosphorylase
Glycogen is synthesized in the cytosol on a primer protein called?
glycogenin
What enzymes transfers glucose residues from UDP-glucose to the nonreducing ends of glycogen chains?
glycogen synthase
Branching is introduced on glycogen by what enzyme?
branching enzyme
When does glycogen degradation occur?
when blood glucose levels are low
What enzyme is the first step in glycogen degradation?
glycogen phosphorylase
What process involves glycogen phosphorylase, phosphoglucomutase, glucose 6 phosphatase and debranchnig enzymes?
glycogen degradation
What process involves hexokinase, phosphoglucomutase , UDP-glucose pyrophosphorylase, glycogen synthase, and branchign enzymes?
glycogen synthesis
During glycogen degradation, what is released from debranched chains of a 1,4 linked glucoses?
glucose phosphates
Glucokinase is NOT inhibited by what product?
gluc 6 phosphate
Glycogen synthase is stimulated by what? Inhibited by what?
+ insulin
- glucagon, epinephrine
Insulin ____ blood sugar concentration.
Glucagon _____ blood sugar concentration.
Epinephrine ____ ATP production from glycogen and glucose.
lowers
raises
stimulates
Can muscles respond to glucagon? Why or why not?
NO!!!! they cannot release glucose as they are lacking glucose 6 phosphatases
In response to epinephrine, what happens in the liver and muscle?
stimulates breakdown of glycogen in the liver
activate glycolysis in the muscle to make ATP