Lipids Flashcards

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1
Q

Functions and properties of triglycerides

A
  • Energy storage
  • Are respired to release energy in the form of ATP
  • Produces around twice as much energy as carbohydrates
  • Insoluble so it doesn’t affect cell’s water potential
  • Stored as adepose tissue when energy input is greater
  • Adepose tissue provides layer of insulation
  • Triglycerides provide protection for
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2
Q

Respiratory substrate

A

Substances used in respiration to release ATP

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3
Q

Types of cholesterol: bad cholesterol

A

Carried in LDL’s
Deposited in arteries
Leads to athlesclerosis
Leads to gallstones

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4
Q

Types of cholesterol: good cholesterol

A

Carried in HDL’s
Removes LDL’s from artery walls
Used to make cell membranes and organelle membranes
Maintains membrane fluidity

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5
Q

Deriratives of cholesterol

A

Testosterone
Oestrogen
Vitamin D
Vitamin A

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6
Q

Functions and properties of phospholipids

A

Form the membrane bilayer
Can change membrane fluidity by increasing he number of unsaturated fatty acids
May have carbohydrates attached to phosphate heads to form a glycolipid
Glycolipds are involved in cell signalling
Amphpathic nature (will mix with water)

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7
Q

Structure of triglycerides

A

Cosists of one olevule of glycerol and fatty acids that are linked to each carbon y ester bonds

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8
Q

Structure of glycerol

A

Has a propane parent chain with alcohol groups on each carbon

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9
Q

General formula for fatty acids

A

CH3(CH2)nCOOH where n>14

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10
Q

What are the two types of fatty acid

A

Saturated and unsaturated

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11
Q

Basic structure of a phospholipid molecule

A

Consists of a glycerol group with two fatty acids and one phosphate group attached
An alcohol group is also attached to the phosphate group

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12
Q

What is an ester bond?

A

The condensation link between an acid group (-COOH) and an alcool group (-OH) by the loss of water

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13
Q

What will a double bond cause in a fatty acid chain?

A

A kink in the chain

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14
Q

The main differences between a triglyceride and a phospholipid molecule

A
  • A phospholipid moecule contains two fatty acid components but a triglyceride contains three
  • A phospholipid contains a phosphate group
  • A phospholipid contains an extra alcohol group attached to the phosphate group
  • The third carbon in the glycerol of a phospholipid is rotated 180 degrees, the glycerol in a triglyceride has all three carbons the same way round
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15
Q

Why are phospholipid molecules amphipathic?

A

The phospholipid head has an alcohol group that can lose a H when in water so the O becomes negatively charged
Therefore the polar head can freely mix with water

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16
Q

What is the phospholipid bilayer chemical comoposition?

A

45% lipid
45% protein
10% polysaccharide

17
Q

What is the thickness of a phospholipid bilayer?

A

7~8 nm

18
Q

What is the impotance of phospholipid molecules in plasma membranes?

A
  • They give the membrane a fluid mosaic structure
  • Allows lipid soluble substances to cross plasma membrane
  • Prevents passage of water soluble substances
  • Phospholipids loosely bond to cholesterol making the membrane stronger and less permeable
19
Q

Why do some membranes have a high proportion of unsaturated fatty acids?

A

The proportion of unsaturated fatty acids will influence flexibility and fluidity.
e.g. membranes of Golgi apparatus and SEM have a higher concentration of unsaturated fatty acids

20
Q

Why are HDL’s better than LDL’s for you?

A

HDL’s remove cholesterol from cells and transport them to be excreted
LDL’s collect cholesterol from blood and deposit tem in cells
Too much cholesterol can lead to atheroma and CHD

21
Q

The eight functions of lipids

A
Energy storage
Strucutral components of membranes
Thermal insulation
Mechanical protection
Electrical insulation
Waterproofing
Buoyancy
Precursors
22
Q

Why are lipids a good source of energy?

A

They contain a lot more energy than carbohydrates

23
Q

How do animals obtain lipids?

A

Lipids are obtained through diet by hydrolysing lipids into glycerol and fatty acids using lipase

24
Q

How and where is the digestion of lipids accelerated?

A

Since lipids are water insoluble, their digestion must be accelerated using bile salts in the large intestine
Bile salts emulsify lipids into smaller particles, greatly increasing the surface area on which lipase can act

25
Q

What do you get when you hydrolyse fats?

A

Fats are hydrolysed to produce fatty acids, monoglycerides and cholesterol

26
Q

How to the epithelial cells of the gut keep the concentration gradient low?

A

The reassembly of triglycerides in the epithelial cells keeps the concentration gradient between the ileum and the epithelial cells low

27
Q

Describe the structure and function of epithelial cells in the gut

A
  • Has many micro-villi to increase surface are to volume ratio
  • Plasma membrane of epithelial cell has protein carriers for active transport
  • Epithelial cells contain SEM for triglyceride sunthesis
28
Q

What are the properties of fatty acids?

A

Can be saturated, monosaturated and polyunsaturated
Animal fats are mainly saturated and solid at room temperature
Unsaturated fats tend to be liquid

29
Q

Function of fatty acids

A

Act as an energy store in most cells

Saturated fats contain more energy due to the increased number of H

30
Q

Properties of triglycerides

A

Depends on the nature of the fatty acid

Animal triglycerides tend to have larger fatty acids and more saturated fatty acids compared to plant lipids

31
Q

Properties of steroids

A

Has a polar head and a non polar tail so it therefore contributes to the membrane bilayer

32
Q

How are trans fats produced?

A

By bubbling hydrogen through unsaturated fatty acids through a process called hydrogenation

33
Q

Why do C=C bonds make a membrane more fluid?

A

C=C double bonds change the shape of the hydrocarbon

These changes in shape cause the molecules to move apart making the membrane more fluid

34
Q

Test for lipids

A

Add ethanol to dissolve lipid and pour alcohol into water in another test tube
If the result tests positive, a white emulsion forms near the top of the water

35
Q

What does essential mean?

A

We cannot make it ourselves so we have to obtain it through diet

36
Q

Why is cholesterol carried as lipoprotein?

A

It is insouble

37
Q

Why does pH fall during the hydrolysis of triglycerides?

A

The concentration of fatty acids increase