Lipid Peroxidation

Question 1

3 Steps of Lipid Peroxidation

Answer 1

1. Initiation
2. Propagation
3. Termination

Question 2

The formation of Reactive Oxygen Species (ROS)

Answer 2

Initiation step of Lipid Peroxidation

Question 3

The following are ROS

Answer 3

1. Singlet oxygen
2. Nitric oxide radical
3. Hydroxyl radical

Question 4

ROS increases the creation of other ROS

Answer 4

Propagation step of Lipid Peroxidation

Question 5

What does the Propagation step of Lipid Peroxidation cause?

Answer 5

• Free radical damage
• Membrane permeability
• DNA damage (nuclear and mitochondrial)
• Create more ROS by lipid peroxidation
• Oxidation of enzymes