Lipid Metabolism III

Question 1

all except one are true about gastric lipase
a) main preduodenal lipase
b) hydrolyzes triglycerides containing short and medium chain fatty acids
c) the primary site of hydrolysis in the SN 3 Ester linkage
d) optimum pH 6-7.0

Answer 1

Optimum pH 6.0-7.0

Question 2

pancreatic juice does not contain, which of the following
a) bile salts
b) phospholipase A2
c) lipase and colipase
d) Lipo protein lipase

Answer 2

lipoprotein lipase

Question 3

Dietary fats are transported as

Answer 3

Chylomicrons

Question 4

One and the only energy requiring step and fatty acid oxidation is catalyzed by which of the following enzyme

Answer 4

Thiokinase

Question 5

A fatty acid with 14 carbon atoms will undergo how many cycles of beta oxidation

Answer 5

6

Question 6

Which statement best describes the oxidation of odd chain fatty acids

Answer 6

end product is propinoyl coA

Question 7

which statement out of the following is incorrect about Zellweger syndrome
a) results from the absence of functional peroxisomes
b) characterized by hypoglycemia and ketosis
c) caused by a defect in the import of enzymes into the peroxisomes
d) death occurs within six years of life

Answer 7

Characterized by hypoglycemia and ketosis

Question 8

what is the molecular basis of the statement fats burn in the flame of carbohydrates?

Answer 8

Acetyl COA is oxidized completely in the presence of oxaloacetate in the TCA cycle

Question 9

which of the following statements correctly describes the enzyme Thiolase
a) it yields acetoacetyl COA as a product
b) it produces Malonyl COA as a product
c) forms COA Ester as a product
d) requires beta keto acyl coA as a substrate

Answer 9

requires beta keto acyl coA as a substrate

Question 10

NADPH required for the fatty acid synthesis can be generated from

Answer 10

HMP pathway

Question 11

which of the following is not used for fatty acid synthesis?
a) cobalamin
b) NADPH
c) biotin
d) bicarbonate

Answer 11

Cobalamine

Question 12

Malonyl CoA is our direct inhibitor of which enzyme of fatty acid oxidation

Answer 12

Carnitine Acyl transferase I

Question 13

when the liver is actively synthesizing fatty acids are concomitant decrease in oxidation of fatty acids is due to

Answer 13

Inhibition of translocation between cellular compartments

Question 14

Which of the following is the primary ketone body?

Answer 14

Acetoacetate

Question 15

all our conditions of ketosis except one
a) starvation
b) uncontrolled diabetes mellitus
c) high carbohydrate diet
d) Von Gierkes disease

Answer 15

Von Gierke disease

Question 16

The key regulatory enzyme of cholesterol synthesis is

Answer 16

HMG coA reductase

Question 17

The key enzyme for the utilization of ketone bodies is

Answer 17

Thiophorase

Question 18

choose the incorrect statement about cholesterol synthesis
a) all the carbon atoms are derived from acetyl COA
b) process process is cytoplasmic
c) NADPH is the main coenzyme
d) highly expensive energetically

Answer 18

Process is cytoplasmic

Question 19

The process by which bile acid sequestrants (food additive) lower serum cholesterol level is

Answer 19

diverse cholesterol metabolism towards bile acid formation