Lipid Metabolism II

Question 1

Which of the following is the best marker for the diagnosis of acute pancreatitis?

Answer 1

amylase

Question 2

A gallstone that blocked the upper part of the bile duct would cause an

Answer 2

Incomplete, lipid digestion, and absorption

Question 3

which of the following molecular complexes in the blood carries the palmitate residue from the lumen of the gut to the surface of gut epithelial cell

Answer 3

Bile salt

Question 4

which of the following supplies all the carbon atoms that are needed for the De Novos synthesis of cholesterol

Answer 4

Acetyl COA

Question 5

which of the following is not needed for the de novo synthesis of fatty acids?

Answer 5

Folic acid

Question 6

substances needed for De Novo synthesis of fatty acids

Answer 6

NADPH, acetyl COA, bicarbonate and ATP

Question 7

which glycolytic intermediate can be used for the synthesis of glycerol 3P

Answer 7

Dihydroxyacetone phosphate

Question 8

which of the following enzymes is required for releasing the newly synthesized fatty acid from the fatty acid synthase complex

Answer 8

Thioesterase

Question 9

Which of the following is the key regulatory enzyme of fatty acid synthesis?

Answer 9

Acetyl COA carboxylase

Question 10

Lipogenesis is increased when sucrose is fed instead of glucose because

Answer 10

Fructose bypasses the phosphofructokinase control point in glycolysis and floods the pathway

Question 11

When stearic acid is oxidized, how many acetyl COA are produced

Answer 11

9

Question 12

an infant is diagnosed with medium chain acyl COA dehydrogenase deficiency what is the biochemical basis of infants symptoms?

Answer 12

Beta oxidation of fatty acid is impaired

Question 13

which of the following is intermediate of pathway of cholesterol synthesis

Answer 13

malonate, squalene, Lanosterol, Desmosterol

Question 14

what are bile salts required for?

Answer 14

Required for digestion and absorption of lipids

Question 15

which of the following Apo proteins is an activator of LCAT

Answer 15

Apo A-I

Question 16

which statement best describes cholesterol ester transfer protein CETP

Answer 16

It exchanges cholesterol esters from HDL for other lipids

Question 17

A patient diagnosed with respiratory distress syndrome due to deficiency of lung surfactant, which of the following is the phosphor, lipid of primary importance in surfactant

Answer 17

Dipmitoyl phosphatidylcholine

Question 18

in a patient with 3 beta hydroxylase deficiency and ambiguous genitalia (lack of androgens) testosterone is produced from which of the following compounds

Answer 18

Cholesterol

Question 19

Aspirin is said to be cardioprotective in myocardial infarction. It is a non-steroidal anti-inflammatory drug that inhibits cyclo oxygenase enzyme. cyclooxygenase required for the production of which compound.

Answer 19

Thromboxane to Arachidonic acid