Fatty acid metabolism Flashcards
glucose can be converted to glycerol 3P through which of the following intermediate?
Dihydroxyacetone phosphate DAP
The conversion of acetyl COA to malonyl COA requires, which of the following
Biotin
NADPH is synthesized by the action of which of the following enzyme
Glucose 6P dehydrogenase
A patient with yellow XANTHOMAS on his skin and hepatomegaly. His triglyceride level is 1500 mg per/DL. He is diagnosed with type V hyperlipidemia triglycerides are primarily synthesized in which of the following tissue.
Liver
Insulin is known to increase the activity of acetyl COA carboxylase. The rate limiting enzyme of fatty acid biosynthesis which of the following describes this regulatory enzyme.
It catalyses a reaction that requires biotin and ATP
The activation of long chain fatty acids requires, which of the following components
2 ATP and CoA
Which statement best describes the beta oxidation of fatty acids
One acetyl coA is produced in each turn of the beta oxidation spiral
Beta oxidation of long chain fatty acids occurs primarily in which of the following locations?
Mitochondria
how many carbons are removed from fatty acyl coA in one turn of the beta oxidation spiral
2
Beta oxidation, of fatty acids is promoted by which of the following
NAD+
what is the role of Theolase in the beta oxidation of fatty acids?
Cleaves the bond between alpha and beta carbons
Which of the following is released in the alpha oxidation of fatty acids
Carbon dioxide
A patient has serum level of ketones and glucose abnormally low. He is diagnosed with carnitine deficiency in which of the following carnitine directly involved.
transport of fatty acyl coA
carnitine acyl transferase I catalyses a reaction that produces which of the following
Fatty acyl Carnitine
how many ATP are produced when Palmitoyl COA is oxidized to CO2 and H2O
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