LFTs

Question 1

Name True LFTs

Answer 1

Bilirubin
Albumin
Prothrombin time (PTT)

Question 2

Cholestatic liver tests

Answer 2

Bilirubin
ALP
y-GT

Question 3

High PTT =

Answer 3

Acute or chronic liver injury

Can also be high if on warfarin

Question 4

Pre-hepatic jaundice =

Answer 4

Unconjugated bilirubin

Question 5

Hepatic jaundice =

Answer 5

Unconjugated bilirubin + Conjugated bilirubin

Question 6

Post-hepatic jaundice =

Answer 6

Conjugated bilirubin

Question 7

What causes pre-hepatic jaundice?

Answer 7

Haemolysis (rupturing of RBC)

Question 8

What causes hepatic jaundice?

Answer 8

A liver not working properly

Question 9

What causes post-hepatic jaundice?

Answer 9

All obstructions of the biliary tree:

• gallstones
• strictures
• tumours

Question 10

Hepatocellular liver tests

Answer 10

Bilirubin
AST
ALT

Question 11

High amylase =

Answer 11

Pancreatitis

Question 12

Presence of Anti-microbial antibodies (AMAs)

Answer 12

Primary Biliary Cirrhosis

Question 13

What is Bilirubinuria?

Answer 13

Conjugated bilirubin in the urine

Question 14

High AST

High ALT

Answer 14

Acute liver injury

if they have similar values, or a 2:1 ratio then this indicated Alcoholic Fatty Liver Disease

Question 15

High ALP

Answer 15

Cholestasis

Can also indicate pregnancy and bone disease/growth

Question 16

High γ-GT

Answer 16

Indicates cholestasis

Question 17

What can high unconjugated bilirubin indicate?

Answer 17

Gilbert’s disease

Question 18

Low Albumin

Answer 18

Indicates chronic liver injury

It’s not acute as albumin has a 20-day half-life

Question 19

Really high ALT/AST + Bilirubin >3mg

Answer 19

Drug causing liver disease

Question 20

Y-GT is high in…

Answer 20

alcoholics