LFT's

Question 1

Where is ALP found

Answer 1

ALP lines the bile ducts

Question 2

When would ALP increase

Answer 2

Damage to the bile ducts

Question 3

Give a definition of Pre-Hepatic Jaundice

Answer 3

Excess unconjugated bilirubin is produced faster than the liver is able to conjugate it. Unconjugated bilirubin is insoluble

Question 4

In Pre-Hepatic jaundice, are both conjugated and unconjugated bilirubin increased?

Answer 4

No
Conjugated bilirubin is normal
Unconjugated bilirubin is increased

Question 5

Give 2 causes of Pre-Hepatic Jaundice

Answer 5

Haemolytic Anaemia

Gilbert’s Syndrome

Question 6

What is Gilbert’s Syndrome

Answer 6

Congenital hyperbilirubinaemia

oi Gilbert

Question 7

What can cause intra-hepatic jaundice

Answer 7

Hepatitis/Cirrhosis

Question 8

What are bilirubin levels like in Intra-Hepatic Jaundice

Answer 8

Increased

Question 9

In Intra-Hepatic jaundice, are both conjugated and unconjugated bilirubin increased?

Answer 9

Yes both are increased

Question 10

What are ALT/AST levels like in Intra-Hepatic Jaundice

Answer 10

Increased

Question 11

What are ALP/GGT levels like in Intra-Hepatic Jaundice

Answer 11

Slightly increased

Question 12

What are urine and stools like in Pre-Hepatic Jaundice

Answer 12

Normal

Question 13

What are urine and stools like in Intra-Hepatic Jaundice

Answer 13

Dark urine and normal/pale stools

Question 14

What are 3 causes of hepatitis

Answer 14

Viral
Drug
Alcoholic

Question 15

What are 3 causes of Intra-Hepatic jaundice

Answer 15

Hepatitis
Cirrhosis
Pregnancy (am I pergenunt?)

Question 16

What can cause Post-Hepatic jaundice

Answer 16

Biliary obstruction

Question 17

In Post-Hepatic jaundice, are both conjugated and unconjugated bilirubin increased?

Answer 17

No
Conjugated bilirubin is increased
Unconjugated bilirubin is normal

Question 18

What are ALT/AST levels like in Post-Hepatic Jaundice

Answer 18

Slightly increased

Question 19

What are ALP/GGT levels like in Post-Hepatic Jaundice

Answer 19

Highly increased

Question 20

What are urine and stools like in Post-Hepatic Jaundice

Answer 20

Dark urine and itchy, pale stools

Question 21

Name 3 causes of post-Hepatic Jaundice

Answer 21

Carcinoma
Gallstones
Pancreatitis

Question 22

What are haemoglobin levels like in the three types of jaundice

Answer 22

pre-hepatic –> Decreased levels
intra-hepatic –> Normal
post-hepatic –> Normal

Question 23

What are the 3 true liver function tests

Answer 23

Bilirubin
Prothrombin time
Albumin

Question 24

What does the true LFT, bilirubin, test

Answer 24

Breakdown of RBC’s

Question 25

What does the true LFT, albumin, test

Answer 25

Chronic hepatocyte function

Question 26

What does the true LFT, prothrombin time, test

Answer 26

Acute hepatocyte function