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Hematology > Leukemia > Flashcards

Leukemia Flashcards

1
Q

Overproduction of immature or mature cells in BM or PB. Malignant cells easily pass the BBB
^ WBC count w/ STTL

A

Leukemia

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2
Q

Solid malignant tumors of the lymph nodes. Distinct cell type is the Lymphocyte

A

Lymphoma

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3
Q

Short duration, Immature cell forms in BM and PB. ^ in total WBC count

A

Acute Leukemias

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4
Q

Long duration,mature cell forms in BM and PB. elevated to lower tha normal WBC count

A

Chronic Leukemias

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5
Q

enzyme found in Primary granules of Eos. Neut. and Monocyte. Used to differentiate blast of AML from ALL

A

MPO

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6
Q

Stains sterols, most sensitive stain for granulocytic prescursor

A

SBB

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7
Q

most common form of childhood leukemia (FAB, use of immunologic markers)

A

ALL

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8
Q

70% of childhood ALL

A

L1

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9
Q

70% of Adult ALL

A

L2

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10
Q

rare in children and adults. Burkitt type of Leukemia

A

L3

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11
Q

most common type of Leukemia in th Elderly.
Characterized by persistent Lymphocytosis, ^ Smudge cells and Reider cell

A

CLL

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12
Q

AML, minimally differentiated
MPO/ SBB (-)

A

M0

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13
Q

AML, w/o maturation
may demonstrate Auer rods

A

M1

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14
Q

AML, With maturation
most common sybtype of AML

A

M2

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15
Q

Acute Promyelocytic Leukemia
Associated w/ DIC, Faggot cells

A

M3

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16
Q

Microgranular variant, cell that have charac. of ‘‘Butterfly/ Bowtie/ coin-on-coin/ apple core’’ nuclei

A

M3V:APL

17
Q

Acute MyeloMonocytic Leukemia
aka. Naegeli Monocytic Leuk.
2nd most common subtype

A

M4

18
Q

Acute Monocytic Leukemia
Shilling leukemia

A

M5

19
Q

AMoL, Poorly diff.
seen in children >80% monoblast in BM

A

M5a

20
Q

AMoL, well diff
seen in middle aged adult <80% monoblast in BM

A

M5b

21
Q

Acute Erythroleukemia
DiGuglielmo’s syndrom
strongly PAS (+)

A

M6

22
Q

Acute Megakaryocytic Leukemia
requires Immunocytochemical staining for accurate diagnosis
Factor VIII stain (+)

A

M7

Hematology (9 decks)

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