Hemoglobin Flashcards

1
Q

Cyanmethemogmobin is measured at

A

540 nm

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2
Q

converts the hemoglobin into methemoglobin

A

Potassium ferricyanide

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3
Q

Full conversion of hemoglobin to cyanmethemoglobin

A

10 minutes at RT

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4
Q

Another technique that has been used in some automated instruments involves the use of

A

Sodium lauryl sulfate

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5
Q

an example of commercially available handheld system to measure the hemoglobin concentration

A

HemoCue

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6
Q

Movement of charged particles in an electrical field

A

Electrophoresis

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7
Q

fastest normal Hb

A

Hemoglobin A1

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8
Q

fast hemoglobin migrate beyond A1

A

Bart Hb
Hb H
Hb I

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9
Q

Slowest abnormal Hb

A

Hb A2
Hb C
Hb E
Hb O
Hb C harlem

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10
Q

Site of heme synthesis

A

Mitochondrion

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11
Q

heme biosynthesis is most prominent in

A

BM and Liver

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12
Q

enzyme needed to insert the Fe2+ to the P IX ring

A

Ferrocheletase (Heme synthetase)

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13
Q

predominant form of Hb in the fetus and newborn

A

Hemoglobin F

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14
Q

Predominant form of Adult hb

A

Hemoglobin A1

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15
Q

hb w/ Fe2+ bound to Carbon Monoxide, 240x greater affinity to Hb than O2

A

Carboxyhemoglobin

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16
Q

Hb w/ Fe2+ NOT bound to O2; other names FERRIHEMOGLOBIN/ HEMOGLOBIN

A

Methemoglobin

17
Q

mixture of oxidized partially denatured forms of Hb some of the causes proloned constipation , C. perfringens

A

Sulfhemoglobin

18
Q

mixture of oxidized partially denatured forms of Hb some of the causes proloned constipation , C. perfringens

A

Sulfhemoglobin