Hematopoiesis Flashcards
Storage of Blood smear slides
7 DAYS
Predominant Hemoglobin during Hepatic Phase
Hb F
Major organ in the body in which antibodies are synthesized from which they are released from the circulation
Spleen
Process of RBC formation that takes place inside the bone marrow
Erythropoiesis
process of RBC formation that takes place inside the bone marrow
Erythropoiesis
Total mass of RBCs circulating in peripheral blood and the Bone marrow RBC precursor
Erythron
erythrocyte in the circulation (only in the blood)
RBC mass
Earliest recognizable erythroid precursor using Light microscope
Rubriblast
LAST stage w/ a NUCLEOLUS, 1st STAGE of Hgb SYNTHESIS
PRORUBRICYTE
Last stage capable of MITOSIS; 1st stage in which the CYTOPLASM becomes PINK
Rubricyte
Last stage w/ a NUCLEUS
Metarubricyte
Nucleus of rubricyte
Checkerboard
Color of the Cytoplasm of Rubricyte
Muddy or Gray
Lymphocte Nucleus
Crushed velvet
Color of the cytoplasm of Lymphocyte
Sky blue
Roin egg Blue
Last stage of Hgb Synthesis, Spends 2-3 days in BM 1 day in PB
Reticulocyte
A flow cytometry based test; most sensitive and specific test to CONFIRM the diagnosis of HS
EMA binding test
Non-oxidative, Anaerobic pathway, produces 2 molecules of ATP
Embden-Meyerhof Pathway
aerobically converts glucose to pentose and produce NADPH
hexose Monophosphate Shunt
aerobically converts glucose to pentose and produce NADPH
hexose Monophosphate Shunt
aerobically converts glucose to pentose and produce NADPH
HMS
aerobically converts glucose to pentose and produce NADPH
HMS
central palloe >1/3 of diameter, usually microcytic
Hypochromic cells
3 key cinical manifestation of Hereditary spherocytosis
Jaundice
Anemia
Splenomegaly