Lesson 1 - chapter 1 Flashcards

1
Q

attempts to explain the specific characteristics and mechanisms of the human body that make it a living being

A

science of human physiology

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2
Q

It links the basic sciences with
medicine and integrates multiple functions of the cells, tissues, and organs into the functions of the living human being.

A

science of human physiology

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3
Q

The basic living unit of the body

Each organ is
an aggregate of many different ___ held together by intercellular supporting structures.

A

cell

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4
Q

red blood
cells, numbering about ___________ in each human being,
transport oxygen from the lungs to the tissues.

A

25 trillion

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5
Q

_______ additional cells of other types perform functions different from those of the red blood cell

A

75 trillion

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6
Q

The entire body, then, contains about
_____ cells

A

100 trillion

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7
Q

cell possesses basic characteristics:

A

For the cell to produce energy in the form of Adenosine triphosphate, oxygen reacts with simplest
structures of fat, carbohydrates, and proteins.

Cells also reproduce and regenerate on their own to
maintain the needed amount in the body.

These cells are suspended in the extracellular fluid (internal
environment), in which its constituents are controlled.

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8
Q

about ____ percent of the adult human body is fluid, mainly
a water solution of ions and other substances.

A

60%

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9
Q

most of the fluid is inside the cells

A

intracellular fluid

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10
Q

1/3 is in the spaces outside the cells and is called

A

extracellular fluid

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11
Q

in constant motion throughout the body.

transported rapidly in the circulating blood and then mixed between the blood and the tissue fluids by diffusion
through the capillary walls.

A

extracellular fluid

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12
Q

here, are the ions and nutrients
needed by the cells to maintain life.

Thus, all cells live in
essentially the same environment

A

extracellular fluid

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13
Q

the extracellular fluid is also called the
internal environment of the body, or the _________

a term introduced more than 150 years ago by the great 19th-century French physiologist ______________

A

milieu intérieur

Claude Bernard
(1813–1878).

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14
Q

Cells are capable of living and performing their special
functions as long as the proper concentrations of _________, ______, _______, _______, _______ and other constituents are available in this INTERNAL environment.

A

oxygen,
glucose,
different ions,
amino acids,
fatty substances

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15
Q

contains large amounts of sodium, chloride, and bicarbonate ions plus nutrients for
the cells, such as oxygen, glucose, fatty acids, and amino acids

A

extracellular fluid

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16
Q

It also contains carbon dioxide that is being transported from the cells to the lungs to be excreted, plus other cellular waste products that are being transported to the kidneys for excretion.

A

extracellular fluid

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17
Q

it contains large amounts of potassium, magnesium, and phosphate ions instead of the sodium and chloride ions found in the extracellular fluid

A

intracellular fluid

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18
Q

In 1929 the American physiologist_________ coined the term homeostasis

A

Walter Cannon (1871–1945)

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19
Q

the maintenance of nearly constant conditions in the internal environment

A

homeostasis

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20
Q

All tissues and organs essentially work
together to achieve a common goal, to maintain a relatively
constant environment

A

homeostasis

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21
Q

various ions, nutrients, waste products, and other
constituents of the body are normally regulated within a
_________, rather than at FIXED VALUES

A

range of values

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22
Q

Variations in blood hydrogen ion concentration are normally less than ________ per liter
(0.000000005 moles per liter).

A

5 nanomoles

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23
Q

few millimoles per liter

1 million times greater than hydrogen ion

A

blood sodium concentration

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24
Q

is often considered to be a state of disrupted
homeostasis

A

Disease

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25
even in the presence of disease, homeostatic mechanisms continue to operate and maintain vital functions through ________.
multiple compensations
26
the discipline of ___________ seeks to explain how the various physiological processes are altered in diseases or injury
pathophysiology
27
✓ Cells are not stagnant; they are ________ because they have to perform the homeostasis to sustain stability and normality
dynamic living units
28
Functional problems are often related to ________ problems
structural
29
2 STAGES OF BLOOD TRANSPORT:
1st stage: Movement of blood throughout the circulatory system 2nd stage: movement of fluid between the blood capillaries and the intercellular spaces between the tissue cells.
30
All the blood in the circulation traverses the entire circuit an average of 1each minute when the body is at rest and as many as _____ times each minute when a person is extremely active
6
31
The capillary walls are permeable to most molecules in the blood plasma, with the exception of __________, which are too large to pass through capillaries readily
plasma proteins
32
There is a continuous exchange of substances between the cells and the interstitial fluid and between the interstitial fluid and the _______.
blood
33
large amounts of fluid and its dissolved constituents that cannot readily pass through the capillaries _________ back and forth between the blood and the tissue spaces
diffuse
34
process of diffusion is caused by ____ of the molecules in both the plasma and the interstitial fluid.
kinetic motion
35
plasma ang IF continue being mixed thereby maintaining _______ of the EXF
homogeneity
36
provides oxygen for the body and removes carbon dioxide.
Respiratory System
37
The blood picks up oxygen in ________ thus acquiring the oxygen needed by cells.
alveoli
38
membrane between the alveoli and the lumen of the pulmonary capillaries
alveolar membrane
39
only 0.4 to 2.0 micrometers thick, and oxygen rapidly diffuses by molecular motion through this membrane into the blood.
alveolar membrane
40
digests foods and facilitates absorption of nutrients. large portion of the blood pumped by the heart also passes through the walls of ______
Gastrointestinal Tract
41
Undigested material that enters the gastrointestinal tract and some waste products of metabolism are eliminated in the __________.
feces
42
It dissolves nutrients, including carbohydrates, fatty acids, and amino acids, that are absorbed from ingested food into the extracellular fluid of the blood
Gastrointestinal Tract
43
metabolizes nutrients changing chemical compositions of absorbed substances to more useful forms.
Liver
44
also eliminates certain waste products produced in the body and toxic substances that are ingested. detoxification or removal of many drugs and chemicals that are ingested.
Liver
45
includes the muscles and bones, tendons, cartilages, and filaments. It is used to obtain food for nutrition and provides motility for protection.
Musculoskeletal System
46
also provides motility for protection against adverse surroundings, without which the entire body, along with its homeostatic mechanisms, could be destroyed
musculoskeletal system
47
ORGANS for Removal of Metabolic End Products
Lungs kidney liver
48
help excrete carbon dioxide from the blood, releasing it to the lung alveoli. breathing out carries carbon dioxide into the atmosphere
Lungs
49
is the most abundant of all the metabolism products.
Carbon dioxide
50
help regulate blood volume and blood pressure
Kidneys
51
One of its main functions is to excrete waste products, slats, water, urea and uric acid, and excess of ions to regulate the EXF composition
Kidneys
52
kidneys perform their function by first filtering large quantities of plasma through the __________ into the TUBULES
glomerular capillaries
53
kidney 2nd process: _______into the blood the substances needed by the body, such as glucose, amino acids, appropriate amounts of water, and many of the ions
reabsorbing
54
end products of cellular metabolism
urea and uric acid
55
performs a distinct function in detoxification, the removal of ingested drugs and chemicals. The end waste products are primarily eliminated in the feces
Liver
56
REGULATION OF BODY FUNCTIONS:
Nervous System Hormone Systems
57
Nervous System is composed of three major parts:
sensory input central nervous system (integrative portion) motor output
58
directs the activity of the muscular system and controls function of many internal organs.
Nervous System
59
detect the state of the body and its surroundings.
Sensory receptors
60
The central nervous system is composed :
brain spinal cord.
61
can store information, generate thoughts, create ambition, and determine reactions that the body performs in response to the sensations.
brain
62
Appropriate signals are then transmitted through the __________ of the nervous system to carry out one’s desires.
motor output portion
63
operates at a subconscious level and controls many functions of the internal organs, including the - level of pumping activity by the heart, -movements of the gastrointestinal tract, and - secretion by many of the body’s glands
autonomic system
64
Located in the body are 8 major ENDOCRINE GLANDS and several organs and tissues that secrete chemical substances called _______
hormones
65
controls many metabolic functions of cells, including growth, rate of metabolism, and activities associated with reproduction. It is being secreted by the endocrine glands.
Hormones System
66
increases the rates of most chemical reactions in all cells, thus helping set the tempo of bodily activity
Thyroid hormone
67
controls glucose metabolism
Insulin
68
control sodium and potassium ions and protein metabolism
adrenocortical hormones
69
controls bone calcium and phosphate.
parathyroid hormone
70
regulates many muscular and secretory activities of the body
nervous system
71
regulates many metabolic functions
hormonal system
72
PROTECTION OF THE BODY:
Immune system integumentary system
73
consists of the white blood cells, tissue cells derived from white blood cells, the thymus, lymph nodes, and lymph vessels that protect the body from pathogens such as bacteria, viruses, parasites, and fungi.
immune system
74
immune system distinguishes its own cells from harmful foreign cells and substances; and destroys the invader by _________ or by producing sensitized lymphocytes or specialized proteins like antibodies that destroy or neutralize the invader
phagocytosis
75
provides protection against injury and foreign invaders.
Integumentary System
76
It includes hair, nails, glands, and other structures. It covers , cushions , and protects the deeper tissues and organs of the body and generally provides a boundary between the body’s internal environment and the out- side world.
integumentary system
77
generally comprises about 12% to 15% of body weight
skin
78
is also important for temperature regulation and excretion of wastes, and it provides a sensory interface between the body and the external environment.
integumentary system
79
provides formation of new beings like ourselves, hence it may sometimes not be considered a homeostatic function, it helps maintain homeostasis holistically
Reproductive System
80
Producing new beings translates to generating new bodies in which ______of additional cells can exist in a well-regulated internal environment.
trillions
81
all body structures are organized to help maintain the _______ & ___________
automaticity and continuity of life
82
control systems operate within the organs to control functions of the individual parts of the organs others operate ______
others operate throughout the entire body to control the INTERRELATIONS between the organs
83
Essential for homeostasis operate in all cells to control IF and EF control interactions among organs
control systems
84
example of control systems of respiratory system, operating in association with the nervous system:
regulates the concentration of carbon dioxide in the extracellular fluid.
85
example of control systems of liver and pancreas
regulate the concentration of glucose in the extracellular fluid, and kidneys regulate concentrations of hydrogen, sodium, potassium, phosphate, and other ions in the extracellular fluid.
86
regulation of oxygen concentration in the tissues is vested principally in the chemical characteristics of hemoglobin
oxygen-buffering function of hemoglobin
87
is a major end product of the oxidative reactions in cells.
Carbon dioxide
88
degree of effectiveness with which a control system maintains constant conditions is determined by the gain of the
negative feedback
89
Any stimulus is counteracted by a response that is going to cause negativity to the initial stimulus
negative feedback
90
anticipate changes brain use this to control to cause the required muscle contraptions.
Feed-forward control systems
91
Most control systems of the body act by ________, which can best be explained by reviewing some of the homeostatic control systems mentioned previously
negative feedback
92
brain corrects the feed-forward signal, it sends to the muscle the next time the movement is going to be required. This process is called __________
adaptive control
93
which is in a sense more or less a delayed negative feedback control
adaptive control
94
can sometimes cause vicious cycles and death, and other times it can be useful.
Positive feedback
95
A system in our body that exhibits the positive feedback response to what we call ______________with changes that amplify the perturbation and therefore leads to INSTABILITY rather than stability.
perturbation
96
· Each functional structure, or organ, helps maintain a constant _______
internal environment
97
As long as _________is maintained, the cells of the body continue to live and function properly.
homeostasis
98
Each cell benefits from homeostasis and in turn, each cell contributes its share toward maintenance of homeostasis.
RECIPROCAL INTERPLAY
99
that provides continuous automaticity of the body until 1 or more functional systems lose their ability to contribute their share of function
reciprocal interplay
100
Extreme dysfunction leads to
death
101