Leptospira

Question 1

Leptospira description eme (3)

Answer 1

Thin,
flexible,
tightly coiled spirals with one or both ends maybe bent to form a hook

Question 2

Leptospira shape

Answer 2

Question mark

Question 3

Leptospira motility

Answer 3

Axial filament

Question 4

Leptospira Specimen (2)

Answer 4

○ Blood and CSF - 1st week/ Acute
○ Urine - 2nd week/ Chronic

Question 5

Leptospira Screening test

Answer 5

MACROscopic agglutination test

Question 6

Leptospira Gold Standard

Answer 6

MICROscopic agglutination test

Question 7

Leptospira Titer

Answer 7

○ ≥ 1:100 - past infection
○ > 1:200 - current infection

Question 8

Leptospira Diseases (5)

Answer 8

Swineherd,
Fort Bragg fever,
Pretibial fever,
Canicola fever,
Autumnal fever

Question 9

Leptospira Culture (2)

Answer 9

○ Fletcher’s medium - for leptospira
■ rabbit serum
■ incubate for 30degC for 6 weeks
○ EJMH - Ellinghausen– McCullough–Johnson– Harris

Question 10

Leptospira MOT

Answer 10

Direct contac

Question 11

● Serovars
● Weil’s disease

Answer 11

L. interrogans var icterohaemorrhagiae

Question 12

L. interrogans var icterohaemorrhagiae stages

Answer 12

○ Anicteric
○ Icteric leptospirosis

Question 13

○ Anicteric (4)

Answer 13

■ self-related
■ mild flu
■ less severe
■ most common stage

Question 14

Icteric leptospirosis (3)

Answer 14

■ weil’s disease
■ multiorgan failure
■ severe

Question 15

L. interrogans var icterohaemorrhagiae Habitat

Answer 15

proximal tubules of kidneys

Question 16

L. interrogans var icterohaemorrhagiae Incubation period

Answer 16

10-12 days