Borrelia

Question 1

Borrelia description (3)

Answer 1

Highly flexible spiral organism - thicker cords
Motile,
Microaerophile

Question 2

Borrelia MOT

Answer 2

arthropods

Question 3

Borrelia Specimen

Answer 3

biopsy and autopsy material

Question 4

Borrelia Stains (3)

Answer 4

○ Modified Steiner - 100% sensitivity for erythema migrans
○ Warthin-Starry
○ Mod. Dierterle Silver stain

Question 5

Quantitative buffy coat (3)

Answer 5

recover borrelia in blood;
more sensitive than blood smear;
aniline dyes

Question 6

Borrelia Culture (2)

Answer 6

○ BSK medium - borrelia burgdorferi
■ 33 degC for 6 weeks
○ Noguchi medium - in ascitic fluid

Question 7

B. burgdorferi disease (2)

Answer 7

● Lyme disease (ECM -erythema chronicum migrans)
● Lyme arthritis

Question 8

Most common tick-borne seen in US

Answer 8

B. burgdorferi

Question 9

Longest and most narrow among borrelia spp

Answer 9

B. burgdorferi

Question 10

B. burgdorferi MOT

Answer 10

ticksz

Question 11

B. burgdorferi stages

Answer 11

○ Stage I - III

Question 12

B. burgdorferi
Stage I

Answer 12

■ bite site
■ ECM

Question 13

B. burgdorferi
Stage II

Answer 13

■ secondary lesions
■ CNS, CVS

Question 14

B. burgdorferi
Stage III

Answer 14

■ chronic arthritis
■ late manifestation

Question 15

B. burgdorferi specimen

Answer 15

Synovial fluid

Question 16

B. burgdorferi Confirmatory tests

Answer 16

Western blot

Question 17

B. recurrentis (3)

Answer 17

● Louse borne
● Epidemic relapsing fever
● Vector/ MOT: louse or human body louse

Question 18

B. turricatae & B. parkeri (3)

Answer 18

● Tick borne
● Endemic relapsing fever
● Soft ticks

Question 19

B. duttoni (4)

Answer 19

● Endemic tick borne relapsing fever
● TBRF
● Commonly seen in Western Africa
● MOT: soft ticks

Question 20

B. hermsii (2)

Answer 20

● North America
● Cornephilus?

Question 21

Avian spirochaetosis

Answer 21

B. anserina