Leprosy Flashcards

1
Q

total number of cases of leprosy worldwide was

A

~18 million

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2
Q

What is the etiological agent of Leprosy

A

Mycobacterium leprae

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3
Q

Describe the etiological agent of Leprosy

A

Gram positive and acid fast, straight/slightly curved rod-shaped bacterium. Cannot be cultured in lab.

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4
Q

what was the experimental animal for leprosy

A

9 Banded armadillo

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5
Q

who discovered Mycobacterium leprae

A

Hansen

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6
Q

what is leprosy also known as

A

Hansen’s Disease

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7
Q

How long can Mycobacterium leprae survive outside the body

A

10 days

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8
Q

How long does it take for this bacterium to divide in host

A

2 weeks

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9
Q

what is the incubation time for Leprosy

A

3 months- 30 years but average 3 years

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10
Q

what percentage of population is susceptible to development of clinical leprosy

A

only 4%

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11
Q

how is leprosy transmitted

A

respiratory route and skin-to-skin contact

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12
Q

where does leprosy tend to show

A

the cooler parts of the body. Hands, feet, limbs, nose

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13
Q

what is the leading cause of morbidity in persons infected with Mycobacterium leprae

A

peripheral sensory nerve damage

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14
Q

with leprosy there is a direct infection of ___ causing nerve damage

A

Schwann cells

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15
Q

what are the two forms of leporsy

A

Tuberculoid and Lepromatous

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16
Q

____ often follows secondary bacterial infections leading to loss of fingers and other extremities

A

Gangrene

17
Q

which form of leprosy do patients suffer from clawed hands , gangrenous fingers and toes, and develop large numb skin plaques

A

Tuberculoid Leprosy

18
Q

which form of leprosy does the skin of the face, arms, and legs become covered in large nodules

A

Lepromatous Leprosy

19
Q

which form of leprosy is the most infectious and is described as “walking cultures”

A

Lepromatous Leprosy

20
Q

what is the treatment for leprosy

A

three antimicrobial agents are used in combination, dapsone, rifampicin. and clofazimne

21
Q

is there a vaccine for leprosy

A

no