Lens and cataract Flashcards
How was the lens formed
from surface ectoderm that is placed in position by infolding
Is the lens thicker anteriorly or posteriorly
anteriorly
Tips of lens fibers meet and form short lines called
suture lines
Highly compacted nuclear lens fibers
nuclear sclerosis
How can you differentiate nuclear sclerosis from cataract
Nuclear sclerosis is transparent and can be seen through with an ophthalmoscope
What percentage of the lens is water
65%
Besides water, what is the other main component of the lens
Protein
What is the lens completely dependent upon for nutrients
the aqueous
Function of the lens
focus light rays on the retina to allow optimal image processing and vision
How is focusing of light achieved
accommodation
What stabilizes and holds the lens in the center of the eye
zonules
Where do zonules attach to the ciliary processes
ciliary body
an eye that lacks a lens
aphakic eye
Too small of a lens
microphakic
too round of a lens
spherophakic
What types of proteins increase and decrease with a cataract
Insoluble increase
soluble decrease
What must be done in order to examine the lens
pupil fully dilated
What effect will a cataract have on PLR
none
Congenital absence of normal tissue
Coloboma
How does a coloboma of the leans appear
flattened region of the equator of the lens
Earliest and smallest cataract you can see
incipient
Cataract with more of the lens involved than incipient. can still see tapetal reflection
Immature
Cataract that looks solid, opaque, white marble. No tapetal reflection or retinal detail can be seen
Mature
With a mature cataract, are PLR’s normal
Yes
Cataract where lens starts to shrink and reabsorb. Difficult to differentiate from mature
Hypermature
Cataract where nucleus liquefies
Morgagnian
Cataract present at birth, nuclear
Congenital
Cataract that occurs in young dogs. Possibly hereditary
Juvenile
Cataract in older dogs. not hereditary
Senile
Most common cause of cataracts in dogs. usually bilateral. usually progress to complete vision loss
Genetic
Abnormal glucose metabolisim in the lens that causes cataract
Diabetic cataract
Rate limiting enzyme for sorbitol pathway
aldose reductase
cataracts common in poodles, labs, irish setters
Secondary to PRA
lens becomes malnourished and accumulates toxins causing cataracts
Secondary to uveitis
Opacity confined to the lens capsule
Capsular cataract
Most of the opacity involves cortex directly beneath lens capule
subcapsular cataract
cataract between capsule and nucleus
cortical cataract
Opacity primarily in the center of the lens. Frequently congenital and nonprogressive
Nuclear
cataract where Most involvement in the area of the lens equator
Equatorial
Focal, central opacity in the center of the visual axis
polar cataract
What is a sign that cataract is actively being produced
when vacuoles are visible
Lens induced uveitis
any cataract will cause inflammation
leakage of lens proteins through the intact lens capsule
Phacolytic uveitis
How should you treat all cataracts larger than incipient in size and for how long
topical anti-inflammatory
rest of life
What drugs are generally safe for long term use
NSAIDS
What can occur when lens-induced uveitis has not been treated and there is chronic inflammation
secondary glaucoma
formation of fibrovascular membrane on the surface of the iris
Pre-iridal fibroVascular membrane
Penetrating trauma to the lens capsule disrupts lends fibers, leading to a cataract
Phacoclastic uveitis
What is performed prior to cataract surgery
electroretinogram or ocular ultrasound
Treatment of choice for lens extration
phacemulsification
Subluxation
lens is partially dislocated
luxation
lens in completely dislocated
are posterior luxations or anterior luxations prefered
Posterior (non-painful)
Lens coming forward and being trapped in the anterior chamber
Primary anterior luxation
Is primary anterior luxation unilateral or bilateral
bilateral
Loss of zonules cause by other intraocular disease
secondary lens luxation
What is the most common cause of lens luxation in cats and horses
Uveitis
what are the best treatments for primary lens subluxation
lifelong topical miotic therapy
surgical removal of the lens