LeDoux- Embryology Flashcards
where do you find pituitary gland
hypophyseal fossa of sella turcica
down growth of diencephalon
pituitary gland
primitive oral cavity (surface ectoderm)
stomodeum
which two structures
infundibulum and Rathke’s pouch
Cells of the anterior wall of Rathke’s pouch increase rapidly and form the _____ of the adenohypophysis
Pars Distalis
extension of anterior lobe that grows along stalk of infundibulum and surrounds it
Pars Tuberalis
The posterior wall of Rathke’s pouch develops into the ______
Pars Intermedia
everything associated w/ anterior lobe is coming from what
Rathke’s pouch (surface ectoderm)
posterior lobe derived from
neuroectoderm
where is this tumor on the R derived from
(craniopharyngioma) derived from surface ectoderm (Rathke’s pouch)
Initially, a solid mass of endodermal cells that are then invaded by vascular mesenchyme
thyroid gland
Initially connected to the foramen cecum by the thyroglossal duct and then it should disappear
thyroid gland
born with no thryoid
growth retardation
mental deficiency
skeletal abnormalities
congenital hypothyroidism (cretinism)
ectopic thyroid tissue
thyroglossal duct cysts
how many and where are the parathyroid glands
2 superior
2 inferior
posterior aspect of thyroid gland
pharyngeal pouches that parathyroid glands arise from
3 and 4
dorsal part of 3rd pouch gives rise to _____ parathyroid glands
inferior
ventral part of 3rd pouch gives rise to _____
thymus
dorsal part of 4th pouch gives rise to ____
superior parathyroid glands
ventral part of 4th pouch gives rise to _____
ultimobranchial body
outer zone of adrenal cortex (name and what it produces)
zona glomerulosa (makes aldosterone)
middle zone of adrenal cortex (name and what it makes)
zona fasciculata; makes cortisol
inner zone of adrenal cortex (name and what it makes)
zona reticularis; makes andogrens
medulla of adrenal gland makes
catecholamines (from neural crest cells)
what generates adrenal cortex and gonads
adrenogonadal primordium
____ zone of the cortex are invaded by neural crest cells and form what _____
Fetal Zone; forms medulla
Toward the end of the third month, a second wave of mesodermal cells penetrates the mesenchyme and surrounds the fetal cortex. These cells form the ____
Definitive Zone of the cortex
____zone mainly responsible for making DHEA (important in maintaining placenta)
Fetal Zone
___ zone is responsible for making cortisol
Definitive zone
____zone responsible for making glucocorticoids
transitional zone
the ______ zone of the cortex regresses at birth, b/c no longer have to maintain placenta
Fetal Zone
doesn’t form until 5-8 years old
zona reticularis
Fetal cortex making way more androgens than its supposed to
In female fetus: will get masculinization of external genitalia
congenital adrenal hyperplasia
(adrenogenital syndrome)
